A commingling analysis of platelet monoamine oxidase activity

A commingling analysis of quantitative neuromuscular performance in a Kansas Mennonite community

“…By convention, r = 6.0 unless x,in < -6.0 (Cf, Morton et al, 1978;Rice et al, 1982). In the present study only one case arose in which the convention was exceeded.…”

Molecular Biology of Monoamine Oxidase A and B: Their Role in the Degradation of Serotonin

“…HOTAMISLIGIL and BREAKEFIELD (1991) provided evidence for a strong correlation between allelic status and MAOA activity, indicating that noncoding, regulatory sequences in the MAOA gene, in part, control enzyme activity. MAOB activity can also vary among control populations (MURPHY et al 1976) and evidence exists for a genetic determinant (RICE et al 1982). However, in contrast to the association of MAOA alleles and activity state, GIRMEN et al (1992) found no correlation of platelet MAOB activity in 41 control males, which suggests that allelic status is not the primary determinant of enzymatic activity.…”

Regulation of Total Leukocyte, Neutrophil and Lymphocyte Concentrations in Human Blood by Major Effectors

“…The SKUMIX computer program was used in several studies to explore the ma jor factor effect for the platelet mono amino oxidase activity [Rice et al, 1982], for plasma uric acid levels [Rao et al, 1982], for lipids and lipoproteins [McGue et al, 1983], and for fat-related measures [Sharma et al, 1984], It was also used as a preliminary step to support the results of segregation analysis for human erythro cyte zinc level and mag nesium level , for the palmar pattern ridge counts [Gilligan et al, 1985] and for hypoalphalipoproteinemia [Borecki et al, 1986]. We found re cently that the number of distributions cal culated by the SKUMIX program corre sponded to the number of the quantitative phenotypes expected in the backcross and intercross offspring of inbred rat strains [Stoic, 1987],…”

“…The skewness was adjusted for by power transformation of the standardized values. The theoretical aspects of the SKUMIX pro gram were discussed recently by several authors [Rice et al, 1982: McGue et al. 1983Sharma et al. 1984], The calculation by SKUMIX program yields seven parameters: e -the common variance: u = the overall mean; t = the displacement between two ex treme means: q = the gene frequency; d «* the dis placement for the middle mean: p = the power trans formation parameter, and F = the inbreeding coeffi cient.…”