A common neural scale for the subjective pleasantness of different primary rewards

Grabenhorst, Fabian; D'Souza, Arun; Parris, Benjamin A.; Rolls, Edmund T.; Passingham, Richard E.

doi:10.1016/j.neuroimage.2010.03.043

Cited by 66 publications

(37 citation statements)

References 69 publications

(92 reference statements)

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“…This, together with manipulation of both reward type and interest rate, allowed us to identify neural planning signals related to behaviorally well-characterized subjective valuations. Although valuations for different reward types typically involve overlapping neural circuits [47, 48], future studies will have to confirm planning signals in saving behavior toward abstract, monetary rewards.…”

Section: Discussionmentioning

confidence: 99%

Neural Basis for Economic Saving Strategies in Human Amygdala-Prefrontal Reward Circuits

2016

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SummaryEconomic saving is an elaborate behavior in which the goal of a reward in the future directs planning and decision-making in the present. Here, we measured neural activity while subjects formed simple economic saving strategies to accumulate rewards and then executed their strategies through choice sequences of self-defined lengths. Before the initiation of a choice sequence, prospective activations in the amygdala predicted subjects’ internal saving plans and their value up to two minutes before a saving goal was achieved. The valuation component of this planning activity persisted during execution of the saving strategy and predicted subjects’ economic behavior across different tasks and testing days. Functionally coupled amygdala and prefrontal cortex activities encoded distinct planning components that signaled the transition from saving strategy formation to execution and reflected individual differences in saving behavior. Our findings identify candidate neural mechanisms for economic saving in amygdala and prefrontal cortex and suggest a novel planning function for the human amygdala in directing strategic behavior toward self-determined future rewards.

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Section: Discussionmentioning

confidence: 99%

Neural Basis for Economic Saving Strategies in Human Amygdala-Prefrontal Reward Circuits

2016

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“…However, although stimulus saliency may be involved in the activation of some areas (e.g., insula, amygdala; Menon and Uddin, 2010), it may not be specific to aversive-related processing. For instance, saliency may also be central in reward-related processing in order to help detect potentially valuable, and thus rewarding, stimuli (see for instance Zink et al, 2004; Grabenhorst et al, 2010). Furthermore, this raises the question regarding the relationship between reward and aversion.…”

Section: Discussionmentioning

confidence: 99%

Identifying a Network of Brain Regions Involved in Aversion-Related Processing: A Cross-Species Translational Investigation

Hayes

Northoff

2011

Front. Integr. Neurosci.

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The ability to detect and respond appropriately to aversive stimuli is essential for all organisms, from fruit flies to humans. This suggests the existence of a core neural network which mediates aversion-related processing. Human imaging studies on aversion have highlighted the involvement of various cortical regions, such as the prefrontal cortex, while animal studies have focused largely on subcortical regions like the periaqueductal gray and hypothalamus. However, whether and how these regions form a core neural network of aversion remains unclear. To help determine this, a translational cross-species investigation in humans (i.e., meta-analysis) and other animals (i.e., systematic review of functional neuroanatomy) was performed. Our results highlighted the recruitment of the anterior cingulate cortex, the anterior insula, and the amygdala as well as other subcortical (e.g., thalamus, midbrain) and cortical (e.g., orbitofrontal) regions in both animals and humans. Importantly, involvement of these regions remained independent of sensory modality. This study provides evidence for a core neural network mediating aversion in both animals and humans. This not only contributes to our understanding of the trans-species neural correlates of aversion but may also carry important implications for psychiatric disorders where abnormal aversive behavior can often be observed.

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“…To investigate whether these independently represented specific reward representations are on a common scale of reward value, we performed an fMRI study in which we were able to show that even fundamentally different primary rewards, taste in the mouth and warmth on the hand, produced activations in the human orbitofrontal cortex that were scaled to the same range as evaluated by reports made during the neuroimaging of the subjective pleasantness of the set of stimuli (Grabenhorst et al, 2010a) (Fig. 11).…”

Section: The Neuroeconomics Of Reward Value In the Orbitofrontal Cortexmentioning

confidence: 99%

“…The regression lines describing the relationship between neural activity (% BOLD signal change) and subjective pleasantness ratings were indistinguishable for both types of reward. Reprinted from Grabenhorst et al (2010a), with permission from Elsevier.…”

Section: The Amygdalamentioning

confidence: 99%

Taste, olfactory, and food reward value processing in the brain

Rolls¹

2015

Progress in Neurobiology

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A common neural scale for the subjective pleasantness of different primary rewards

Abstract: A common neural scale for the subjective pleasantness of different primary rewards, NeuroImage (2010),

Cited by 66 publications

References 69 publications

Neural Basis for Economic Saving Strategies in Human Amygdala-Prefrontal Reward Circuits

Neural Basis for Economic Saving Strategies in Human Amygdala-Prefrontal Reward Circuits

Identifying a Network of Brain Regions Involved in Aversion-Related Processing: A Cross-Species Translational Investigation

Taste, olfactory, and food reward value processing in the brain

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