The paper provides an overview of research (analytical, numerical, and experimental methods) related to the stress state of artillery projectiles during movement through the barrel of the weapon. The characteristics of the 155mm HERA M549 and 155mm HE M795 projectiles, used in numerical simulations, are described. As a main goal of the research, numerical simulations were performed with the 155mm projectiles to determine the maximum equivalent stresses that occur during the launch of this ammunition. The obtained values were compared with the yield limit of the materials of the projectile components, in order to assess whether the plastic deformation would occur during the launch phase.