A comparative analysis of functional outcomes in adolescents and young adults with lower‐extremity bone sarcoma

Ginsberg, Jill P.; Shesh, N.; Carlson, Claire A.; Meadows, Anna T.; Hinds, Pamela S.; Spearing, Elena M.; Zhang, Lijun; Callaway, Lulie; Neel, Michael D.; Rao, Bhaskar N.; Marchese, Victoria

doi:10.1002/pbc.21018

Cited by 106 publications

(123 citation statements)

References 32 publications

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“…Three publications included an objective, quantitative functional measure [4,10,15]. The one publication that compared AKA only and LSS using an objective measure identified superior physical function in the LSS group [10]. Our study provides additional data to support the lack of quality-of-life difference between these treatment groups.…”

Section: Discussionmentioning

confidence: 61%

“…Only one of 11 publications observed a difference in quality-of-life scores between the two groups [15]. Three publications included an objective, quantitative functional measure [4,10,15]. The one publication that compared AKA only and LSS using an objective measure identified superior physical function in the LSS group [10].…”

Section: Discussionmentioning

confidence: 99%

“…subjective questionnaire data as assessed with the Musculoskeletal Tumor Society (MSTS) score [2,15,16,26,28,34] and objective measurements of functional capacity [4,10]. Given the limited information, particularly regarding objective functional measurements, we thought it important to confirm these observations.…”

Section: Introductionmentioning

confidence: 99%

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Does Limb-salvage Surgery Offer Patients Better Quality of Life and Functional Capacity than Amputation?

Malek

Somerson

Mitchel

et al. 2012

Clinical Orthopaedics &Amp; Related Research

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Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 99%

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Does Limb-salvage Surgery Offer Patients Better Quality of Life and Functional Capacity than Amputation?

Malek

Somerson

Mitchel

et al. 2012

Clinical Orthopaedics &Amp; Related Research

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“…Endoprosthesis alternatives must be considered. Amputation and rotationplasty are alternatives to limb-preservation surgery [4,12,22,30]. These surgeries require the patient to use an external prosthesis for ambulation.…”

Section: Discussionmentioning

confidence: 99%

“…Numerous small series have compared patient function, quality of life, and reconstruction longevity after expandable endoprosthesis and amputation or rotationplasty with external prosthesis; no one option has presented as a clear winner [4,12,21,27,29]. Lacking from these analyses has been any mention of the expense of these implants.…”

Section: Discussionmentioning

confidence: 99%

What are Estimated Reimbursements for Lower Extremity Prostheses Capable of Surgical and Nonsurgical Lengthening?

Henderson

Pepper

Letson

2012

Clinical Orthopaedics &Amp; Related Research

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Background Growing prostheses accommodate skeletally immature patients with bone tumors undergoing limbpreserving surgery. Early devices required surgical procedures for lengthening; recent devices lengthen without surgery. Expenses for newer expandable devices that lengthen without surgery are more than for their predecessors but overall reimbursement amounts are not known.Questions/purposes We sought to determine reimbursement amounts associated with lengthening of growing prostheses requiring surgical and nonsurgical lengthening. Methods We retrospectively reviewed 17 patients with growing prostheses requiring surgical expansion and eight patients with prostheses capable of nonsurgical expansion. Insurance documents were reviewed to determine the reimbursement for implantation, lengthening, and complications. Growth data were obtained from the literature. Results Mean reimbursement amounts of surgical and nonsurgical lengthenings were $9950 and $272, respectively. Estimated reimbursements associated with implantation of a growing prosthesis varied depending on age, sex, and location. The largest difference was found for 4-year-old boys with distal femoral replacement where reimbursement for expansion to maturity for surgical and nonsurgical lengthening prostheses would be $379,000 and $208,000, respectively. For children requiring more than one surgical expansion, net reimbursements were lower when a noninvasive lengthening device was used. Annual per-prosthesis maintenance reimbursements to address complications for surgical and nonsurgical lengthening prostheses were $3386 and $1856, respectively.

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Vinorelbine, doxorubicin, and prednisone in androgen‐independent prostate cancer

Borden

Clark

Lovato

et al. 2006

Cancer

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Background To examine the practical applicability, internal consistency, and validity of the Bt‐DUX, a disease‐specific Health Related Quality of Life (HRQoL) instrument. The Bt‐Dux was developed to examine patients' individual values of their life after a malignant bone tumor of the lower extremity at four domains (cosmetic, social, emotional, and functional). Procedure Patients were eligible for this cross‐sectional, multicenter study if they underwent surgery for a malignant tumor of the leg in a period ranging between 12 and 60 months before the recruitment. Assessments included: Bt‐DUX, Toronto Extremity Salvage Score (TESS) Short Form (SF)‐36, TNO‐AZL Questionnaire for Adult's Quality of Life (TAAQOL), and TNO‐AZL Children's Quality of Life Questionnaire (TACQOL). Results Seventy‐two patients (35 male, 37 female), mean age 17 (SD 4) years were included. Limb sparing surgery took place in 32 patients and ablative surgery in 40 patients. The Bt‐DUX was completed in less than 5 min and easy to comprehend. The mean Bt‐DUX score was 69.8 (SD 15.5), with Cronbach's alpha being 0.92. Domain–total correlations ranged between 0.84 and 0.88 (P < 0.01). Correlations between Bt‐DUX Total score and TESS, SF‐36 Physical and Mental Component Summary scales and selected TACQOL and TAAQOL scores were statistically significant (P < 0.05), except for the social scale of the TACQOL. The Bt‐DUX was able to discriminate between patients with higher and lower TESS scores (P < 0.05). Conclusion The Bt‐DUX was found to be a practical and valid instrument. Its added value compared with existing HRQoL measures needs to be further established. Pediatr Blood Cancer 2009;53:348–355. © 2009 Wiley‐Liss, Inc.

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A comparative analysis of functional outcomes in adolescents and young adults with lower‐extremity bone sarcoma

Cited by 106 publications

References 32 publications

Does Limb-salvage Surgery Offer Patients Better Quality of Life and Functional Capacity than Amputation?

Does Limb-salvage Surgery Offer Patients Better Quality of Life and Functional Capacity than Amputation?

What are Estimated Reimbursements for Lower Extremity Prostheses Capable of Surgical and Nonsurgical Lengthening?

Vinorelbine, doxorubicin, and prednisone in androgen‐independent prostate cancer

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