A Comparative Diagnostic Study for Using the Contrast Agent in Active and Non-Active Multiple Sclerosis by Region of Interest Parameter

Abstract

Background: Multiple sclerosis (MS) is a neuropathological disease diagnosed by a magnetic resonance imaging device. Early patients affected with MS are named active. Objectives: This study assessed the difference between active and non-active MS using the region of interest value. Methods: Twenty patients with MS included in this study were examined with T1 weighted image (T1W) with and without contrast agent injection to increase the brightness of darker regions after only 10 minutes. Also, T2 weighted images (T2W) and Fluid-attenuated inversion recovery (FLAIR) were scanned. The area of interest option was calculated for all cases. Results: The result shows that the region of interest (ROI) value was significantly higher for T1 weighted image (T1W) with contrast than without. Furthermore, the range of FLAIR values was higher than the (T2W). Conclusion: The ROI is an effective parameter for diagnosing active MS early by values instead of the radiographic picture.