A Comparative efficacy of Aceclofenac and Ibuprofen in Post-operative Pain after Lower Third Molar Surgery - A Clinical Study

Chitlangia, Punit; Hemavathi, K. B.; Narad, Chintan; Saini, Savita

doi:10.5958/j.2320-5962.1.2.039

Cited by 2 publications

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“…It is noticed that pain after removal of third molars is of short duration and attains the maximum intensity in the post-operative period (Chitlangia et al, 2013). The experience of pain is useful, especially for examining the single doses of analgesics ef icacy.…”

Section: Resultsmentioning

confidence: 99%

A Comparison of Pre-emptive Analgesic Efficacy of Aceclofenac and Piroxicam for Post-Operative Pain Management after third Molar Surgery: A Prospective, Randomized, Double-blind Study

Jayabalan

Muthusekhar

2020

ijrps

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The study aimed to compare the analgesic efficacy of 100 mg and 20 mg as a analgesic for preventing post-operative pain after third molar surgery. Fifty patients with impacted mandibular third molars who required surgical removal were included in the study. These patients were divided into two groups randomly. One group consisted of patients receiving 100 mg as a analgesic, and the other group consisted of patients receiving 20 mg as a analgesic 1 hour before the procedure. The study findings show both the drugs were equally effective in managing post-operative pain following third molar surgery. On statistical analysis, there was no significant difference in pain experience among both groups A and B in post-operative period who underwent surgery. However, the study observes a highly significant difference in both the groups in terms of pain intensity scores at different times. Results show that there was a significant difference before, 3rd day and 5th day; Further study shows that the effectiveness of the drug was not confirmed in 24 hours to 3 days. It was observed both the groups shows a significant difference in on the 5thand 3rd day. This comparative research of pain intensity shows after analgesia with and in of third molars, a pronounced effect in the group treated with 20mg was seen. Still, there was no statistically significant difference noted in VAS before and 5th day of both groups.

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Section: Resultsmentioning

confidence: 99%

A Comparison of Pre-emptive Analgesic Efficacy of Aceclofenac and Piroxicam for Post-Operative Pain Management after third Molar Surgery: A Prospective, Randomized, Double-blind Study

Jayabalan

Muthusekhar

2020

ijrps

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“…17 Pain after removal of impacted third molars is of short duration, usually accompanied by buccal swelling and trismus and reaches its maximum intensity at 4 -6 hours postoperatively. 4,9,18 There is predictable development of pain and inflammation in TMS, and usually it is performed in young patients without systemic pathology. Hence, the pain management in third molar surgery has become an efficient analgesic testing model.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Efficacy of Aceclofenac and Ibuprofen After Surgical Removal of Impacted Third Molar

Agarwal¹,

Chattopadhyay²,

Mandal³

2017

jemds

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BACKGROUND The removal of impacted mandibular third molar is one of the most frequently performed oral surgical procedure, which leads to severe pain and swelling owing to trauma and inflammation of soft tissue and bone. The quality of life after lower third molar surgery is affected three times more in patients with pain, swelling and trismus alone or in combinations. Postoperative pain after third molar surgery is often used as a model to test the efficacy of analgesics. Despite existence of several studies, no analgesics has won the certificate of excellence and the quest is still on to find out a better agent in this aspect. MATERIALS AND METHODS The present study was aimed at evaluating ibuprofen and aceclofenac, among 100 patients regarding the individual efficacies and to compare between the two drugs in reducing postoperative facial swelling, pain and trismus after removal of mandibular third molars. The patients were randomly divided into two groups to receive either ibuprofen 400 mg (Group A, n = 50) or aceclofenac 100 mg (Group B, n = 50), each drug 8 th hourly for three days postoperatively. Facial swelling, pain and mouth opening scores were recorded on the first, second, fifth and seventh postoperative days. RESULTS Both the drugs were found to be effective in controlling postoperative facial swelling, pain and mouth opening compared with their own baseline measurements. Relief of pain and trismus were found better in patients receiving ibuprofen (400 mg) compared with aceclofenac (100 mg), while control of facial swelling was found comparable between the groups. CONCLUSION The study concludes that both ibuprofen (400 mg) and aceclofenac (100 mg) are effective in controlling postoperative swelling, pain and trismus after surgical removal of impacted lower-third molars. Ibuprofen is better than aceclofenac in alleviation of pain and trismus. Control of facial swelling is comparable with the use of both drugs. A dose-response study and evaluation of different drug formulations of these molecules are warranted in such surgical setting in future.

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A Comparative efficacy of Aceclofenac and Ibuprofen in Post-operative Pain after Lower Third Molar Surgery - A Clinical Study

Cited by 2 publications

References 0 publications

A Comparison of Pre-emptive Analgesic Efficacy of Aceclofenac and Piroxicam for Post-Operative Pain Management after third Molar Surgery: A Prospective, Randomized, Double-blind Study

A Comparison of Pre-emptive Analgesic Efficacy of Aceclofenac and Piroxicam for Post-Operative Pain Management after third Molar Surgery: A Prospective, Randomized, Double-blind Study

Comparison of Efficacy of Aceclofenac and Ibuprofen After Surgical Removal of Impacted Third Molar

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