A comparative evaluation of cataract classifications based on shear-wave elastography and B-mode ultrasound findings

Özgökçe, Mesut; Batur, Muhammed; Alpaslan, Muhammed; Yavuz, Alpaslan; Batur, Abdüssamet; Seven, Erbil; Arslan, Harun

doi:10.1007/s40477-019-00400-6

Cited by 14 publications

(5 citation statements)

References 18 publications

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“…SWE imaging technology is a real-time, noninvasive form of sonoelastography [6,7]. The SWE technique allows for quantitative assessment [meters per second (m/s) and/or kilopascal (kPa)] of tissues according to their stiffness, providing data on histologic changes in tissues and assisting in differential diagnosis [8][9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of perforating venous insufficiency with shear wave elastography: a preliminary study

Durmaz

Kesimal²,

Ünal

et al. 2020

J Ultrasound

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Purpose The aim of this study was to investigate the efficacy of shear wave elastography (SWE) in the diagnosis of perforating vein insufficiency, and to determine the applicability of these measurements. Methods A total of 140 symptomatic patients with a total of 280 lower extremities were investigated. All patients presented with venous insufficiency (VI) symptoms, and received Doppler ultrasound assessment to determine VI and SWE measurements. The SWE values were measured in the adjacent perivenous tissue of the largest Cockett's perforating vein (PV) of both lower extremities, at the level where they pass the fascia. The Cockett's PV diameter and the presence of reflux in Cockett's PV and the great saphenous vein were compared with SWE values in perivenous tissue of PVs. ResultsThe SWE values of the perforating vein insufficiency group were significantly higher than those of the normal PV without insufficiency group (P < 0.001). A significant and positive relation was seen between increased PV diameter and SWE values (P < 0.001) and there was a significant relationship between the presence of perforating vein insufficiency and increase in PV diameter. A statistically significant increase was detected in SWE values for the PV for those with reflux in the great saphenous vein (P < 0.001). The best cut-off values that can be used to detect perforating vein insufficiency were found 34.600 for kPa and 3.375 for m/s. Conclusion SWE may be used effectively in addition to conventional Doppler ultrasound examination in diagnosing and following perforating vein insufficiency.

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Section: Introductionmentioning

confidence: 99%

Evaluation of perforating venous insufficiency with shear wave elastography: a preliminary study

Durmaz

Kesimal²,

Ünal

et al. 2020

J Ultrasound

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“…The lenses are losing their elasticity and become very stiff. Although the relationship between lens stiffness and age is currently well known [27][28][29][30][31], studies on the influence of cataract formation on lens stiffness are still limited [30,56]. Based on our previous results and this study, both cold and oxidative cataracts cause the lens to become stiffer, and the changes in stiffness correlate with the changes in lens opacity [47].…”

Section: Discussionmentioning

confidence: 59%

Elasticity Changes in the Crystalline Lens during Oxidative Damage and the Antioxidant Effect of Alpha-Lipoic Acid Measured by Optical Coherence Elastography

et al. 2021

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Age-related cataracts are one of the most prevalent causes of visual impairment around the world. Understanding the mechanisms of cataract development and progression is essential to enable early clinical diagnosis and treatment to preserve visual acuity. Reductive chemicals are potential medicines effective on cataract treatment. In this work, we investigated the cataract-induced oxidative damage in the crystalline lens and a kind of reductant, α-lipoic acid (ALA), ability to reduce the damage. We created oxidative environment to investigate the relationship between the progression of oxidative cataract and lenticular biomechanical properties measured by dynamic optical coherence elastography in porcine crystalline lenses ex vivo. The efficacy of ALA to minimize the stiffening of the lens was also quantified. The results showed a significant increase in Young’s modulus of the lens due to the formation of the oxidative cataract. We found a statistically significant difference between Young’s modulus of the lenses stored in phosphate-buffered saline and ALA solution after incubation in H2O2 solution for 3 h (43.0 ± 9.0 kPa versus 20.7 ± 3.5 kPa, respectively). These results show that the lens stiffness increases during oxidative cataract formation, and ALA has the potential to reverse stiffening of the lens caused by oxidative damage.

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“…In a study carried out by Mesut Ozgokce et al [ 28 ], no significant difference in the mean shear-wave velocity was shown between patients with senile cataracts and normal subjects. Conversely, Zhou et al [ 29 ] found that advancing age correlates with a significant decrease in the lens nucleus strain rate ratio, indicating increased lens nucleus stiffness.…”

Section: Discussionmentioning

confidence: 98%

Feasibility of shear wave elastography for evaluating lens stiffness in patients with age-related cataracts: A quantitative analysis

Qiang,

Xu,

et al. 2024

Heliyon

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A comparative evaluation of cataract classifications based on shear-wave elastography and B-mode ultrasound findings

Cited by 14 publications

References 18 publications

Evaluation of perforating venous insufficiency with shear wave elastography: a preliminary study

Evaluation of perforating venous insufficiency with shear wave elastography: a preliminary study

Elasticity Changes in the Crystalline Lens during Oxidative Damage and the Antioxidant Effect of Alpha-Lipoic Acid Measured by Optical Coherence Elastography

Feasibility of shear wave elastography for evaluating lens stiffness in patients with age-related cataracts: A quantitative analysis

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