A comparative immunocytochemical study of the gastro-entero-pancreatic (GEP) endocrine system in a stomachless and a stomach-containing teleost

Abad, María Eugenia; Binkhorst, Floor; Elbal, M.T.; Rombout, J.H.W.M.

doi:10.1016/0016-6480(87)90357-1

Cited by 49 publications

(27 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cholecystokinin‐8 is a major gastrointestinal hormone that stimulates pancreatic secretion and gall bladder contraction, regulates gastrointestinal motility and inhibits gastric emptying (Jönsson, Holmgren & Holstein 1987). In many fish, CCK‐8 has been recorded in ECs of the stomach and proximal intestine (Abad et al 1987; Jönsson et al 1987; Elbal, Lozano & Agulleiro 1988; Reinecke et al. 1997).…”

Section: Discussionmentioning

confidence: 99%

Influence of enteric helminths on the distribution of intestinal endocrine cells belonging to the diffuse endocrine system in brown trout, Salmo trutta L.

Dezfuli

Giari

Arrighi

et al. 2003

Journal of Fish Diseases

View full text Add to dashboard Cite

The presence of intestinal helminths in the alimentary canal of brown trout, Salmo trutta L., can alter the number of cells that synthesize modulatory peptides. A total of 167 brown trout were collected from tributaries of the River Brenta (northern Italy), of which 119 (71.3%) specimens were infected with enteric helminths, 28 with the acanthocephalan Pomphorhynchus laevis Müller, 1776 with intensity of infection ranging from 1 to 162 (18.57 +/- 30.79) worms per host and 67 fish with the cestode Cyathocephalus truncatus Pallas, 1781. Intensity of infection with C. truncatus ranged from 1 to 85 (6.87 +/- 12.59) per fish. In 24 fish there were concurrent infections of both species of helminths. The caecal and middle regions of the intestine were the most heavily parasitized. Immunohistochemical tests showed a decrease in endocrine cells (ECs) of the diffuse endocrine system (DES) positive to gastrin, cholecystokinin-8, bombesin and secretin antisera in the intestine of the infected trout. The number of ECs immunoreactive to anti-glucagon serum did not show differences in the digestive tract of uninfected brown trout and in conspecifics parasitized with P. laevis. The density of cells containing glucagon-like material was low in the fish parasitized with C. truncatus. The results suggest that endoparasitic helminths induce alterations in the DES of infected S. trutta.

show abstract

Section: Discussionmentioning

confidence: 99%

Influence of enteric helminths on the distribution of intestinal endocrine cells belonging to the diffuse endocrine system in brown trout, Salmo trutta L.

Dezfuli

Giari

Arrighi

et al. 2003

Journal of Fish Diseases

View full text Add to dashboard Cite

show abstract

“…Co-localization of peptides belonging to the GLUC and PP families has been observed in the human embryonic and adult pancreas (Herrera et al 1991), in teleosts (Abad et al 1987(Abad et al , 1988Lozano et al 1991b;Beolegui et al 1992;Agulleiro et al 1993), and in the lamprey (Cheung et al 1991). Different theories have been proposed to explain the coexistence of GLUC and PP peptides.…”

Section: Discussionmentioning

confidence: 94%

Fine structure and immunocytochemistry of cells within the endocrine pancreas of the gar (Lepisosteus osseus)

Groff¹,

Youson²

1998

Can. J. Zool.

View full text Add to dashboard Cite

Routine electron microscopy and immunocytochemistry were used to describe the cell types in the islets of the endocrine pancreas of the gar Lepisosteus osseus, an actinopterygian fish of the order Semionotiformes, which has an ancient lineage. The general fine-structural features of cells composing the islets reflect their synthesis and packaging of protein for liberation at their perivascular surface. Cells are directly apposed to numerous capillaries and they are richly innervated with nerve terminals containing dense-cored vesicles. The islet tissue comprises many B cells, which are easily distinguished by their ubiquitous granules with polymorphous matrix cores and a loose-fitting membrane. These granules are only immunoreactive with an insulin antiserum. Only one type of D cell is found throughout the islets and it contains many granules of varying electron density, the most abundant granule profile being dumbbell-shaped. All granules in this cell type have a tight-fitting limiting membrane and they immunostain with antisomatostatin-14 and -34. Cells at the periphery of the islet contained granules of similar morphology to those in the D cells, but the granules were less numerous. Many granules in the cells were immunoreactive with both antiglucagon and antineuropeptideY, while others immunostained with only one of these antibodies. Since no cells stained exclusively for either glucagon or neuropeptide Y, it was concluded that there are only three cell types in the endocrine pancreas of the gar: B and D cells and a third cell type (A/F) that co-localizes peptides of the glucagon and pancreatic polypeptide family. Although this co-localization is not uncommon in the vertebrate endocrine pancreas, it may have some phylogenetic and (or) ontogenetic significance in this organism.

show abstract

“…There a r e pancreatic tissue scattered diffusely in the mucosal lining of the intestine. The relationship of the pancreatic islet to exocrine tissue or its equivalent is variable among bony, cartilaginous and agnathan fishes (Youson and Mahroukia, 1999): Although there is a common progenitor for endocrine and exocrine cells, they can be completely separate organs along the gastrointestinal tract in different species of fish (Abad et al, 1987). Therefore, the present study was carried out to investigate the obvious differences between the pancreas of Caspian sea Huso huso and other fish species.…”

Section: Introductionmentioning

confidence: 96%

Study of Pancreas in“Huso huso”

Saadatfar¹,

Shahsavani

Taevighi³

2007

Journal of Applied Animal Research

View full text Add to dashboard Cite

A comparative immunocytochemical study of the gastro-entero-pancreatic (GEP) endocrine system in a stomachless and a stomach-containing teleost

Cited by 49 publications

References 43 publications

Influence of enteric helminths on the distribution of intestinal endocrine cells belonging to the diffuse endocrine system in brown trout, Salmo trutta L.

Influence of enteric helminths on the distribution of intestinal endocrine cells belonging to the diffuse endocrine system in brown trout, Salmo trutta L.

Fine structure and immunocytochemistry of cells within the endocrine pancreas of the gar (Lepisosteus osseus)

Study of Pancreas in“Huso huso”

Contact Info

Product

Resources

About