2024
DOI: 10.4103/drj.drj_666_23
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A Comparative immunohistochemical analysis of epithelial–mesenchymal transition biomarkers in odontogenic keratocyst, dentigerous cyst, and radicular cyst

Hamideh Kadeh,
Nahid Esmaeilzadeh Ashini

Abstract: Background: Odontogenic keratocyst (OKC) is one of the common odontogenic cysts with aggressive clinical behavior and a high recurrence rate. Epithelial–mesenchymal transition (EMT) is a process, in which the epithelial cell loses its epithelial characteristics and acquires mesenchymal features. Since the evidence for the involvement of EMT in the development of OKC is still limited, the present study aimed to investigate the immunohistochemical expression of EMT-related proteins (E-cadherin and N-… Show more

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