A Comparative Pathomorphological Findings Between Leiurus abdullahbayrami and Androctonus crassicauda (Scorpion: Buthidae) Envenomation in Rabbit Animal Model

Abstract

Background: The aim of study was to compare macroscopical and histopathological findings between venoms be-longing to two scorpion species, Androdoctonus crassicauda, and the newly discovered Leirus abdullahbayrami.
 Methods: The animals used in this experimental study were fifteen New Zealand bred rabbits. Three groups were constituted as group I (L. abdullahbayrami group, n= 6), group II (A. crassicauda group, n= 6) and group III (control group, n= 3). The animals in the L. abdullahbayrami group and the A. crassicauda group were envenomed through an intravenous route. The rabbits were monitored for the first 24h following the envenomation. The animals dead within that time period were examined and all animals were sacrificed and standard necropsy process was performed at 24h.
 Results: The pathomorphological findings from group I were found to be more severe than those observed in group II. The venom from the newly identified L. abdullahbayrami has a greater effect than the venom from the A. crassicauda. Moreover, as this was a rabbit modeling study, the L. abdullahbayrami might pose the most serious health threat to infants in particular due to their smaller body weight.
 Conclusion: These findings will provide a better understanding of envenomation of human beings in terms of the possible consequences of scorpion toxication on the organs.

Androctonus crassicauda Zehirinin Gebe Sıçanlar ve Yavruları Üzerine Etkileri

“…A. crassicauda is one of the most venomous scorpions in the world, and that includes Turkey [4][5][6][7] . In this research, we chose repetitive doses of the venom because there have been reports of more than one scorpion sting of a pregnant woman in Turkey.…”

“…In addition to Turkey, the same scorpion can be found in Jordan, Syria, Iran, Iraq and Saudi Arabia and is medically important in these countries as well [5] . In Turkey, A. crassicauda is the most significant scorpion species responsible for scorpion sting cases and for antivenom production.…”

“…In addition, depending on the structure of the culture and socio-economic characteristics, many women work outdoors, particularly in the southeastern region of Turkey, thus the probability of scorpion stings increases among females. Indeed, many demographic reports in the country confirm that over 50% of scorpion sting cases occur in females [5][6][7] . As a result, it should be remembered that pregnant women are potential victims.…”

Discrimination of two species (Androctonus crassicauda and Leiurus abdullahbayrami; Buthidae Scorpions) by MALDI-TOF- MS-based PCA

“…It is known as the yellow scorpion, which lives endemic in Syria and Turkey (in the Southeast Anatolia region). Androctonus crassicauda (ACR), known as the black scorpion, is widely found in North Africa, the Middle East and Asia [5].…”