A Comparative Review of Pharmacoeconomic Guidelines

Jacobs, Philip; Bachynsky, John; Baladi, Jean-Francois

doi:10.2165/00019053-199508030-00002

Cited by 55 publications

(24 citation statements)

References 3 publications

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“…During the past few years guidelines for economic evaluation of pharmaceutical products have been developed in Australia, Canada, England and Wales [21], Similar guidelines for evaluating treatm ent and rehabilitation of diseases would be most useful.…”

Section: Discussionmentioning

confidence: 99%

Cost-of-lllness Studies of Stroke

Porsdal

Boysen

1997

Cerebrovasc Dis

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Stroke accounts for a significant proportion of the expenditures in the health care and social service sectors. Health economics studies of stroke have been performed in several countries. A selection of cost-of-illness studies of stroke from Europe, the USA and New Zealand were reviewed concerning methods of costing. The methodological differences between the studies are significant and this severely limits the possibility of comparing the results. Obtaining consensus on methodology is necessary to make future studies comparable.

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Section: Discussionmentioning

confidence: 99%

Cost-of-lllness Studies of Stroke

Porsdal

Boysen

1997

Cerebrovasc Dis

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“…In general, guidelines [12]recommend the use of trial-based data, supplemented by modelling in order to replicate (long-term) effects of the actual practice conditions. A model is a simplified version of reality that is used to describe the essential elements of a real situation such as the economic implications of using a particular stroke therapy.…”

Section: Study Framementioning

confidence: 99%

“…Furthermore, a number of countries [12, 60, 61], in most instances initiated by the government, have created guidelines. In general, these guidelines try to improve the use of economic evaluation for both reimbursement and listing purposes.…”

Section: Adaptation and Utilizationmentioning

confidence: 99%

“…Broadly, these guidelines incorporate common features mentioned in this article. Although there are several differences, all guidelines underline the importance of using and reporting transparent methods so that readers can easily understand what calculations are being performed on which data elements, minimizing bias, and providing justification for the methods and assumptions used [12, 61]. …”

Section: Adaptation and Utilizationmentioning

confidence: 99%

“…Figure 1 gives an indication of the growth in quantity and does not give any indication whatsoever of the enlargement in quality. The importance of economic evaluation studies can also be illustrated by the fact that some governments have developed guidelines for economic evaluation of pharmaceutical products before listing and pricing a drug [10, 11, 12]. …”

Section: Introductionmentioning

confidence: 99%

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Economic Evaluation in Stroke Research

Evers

Goossens²,

Ament

et al. 2001

Cerebrovasc Dis

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Background and Purpose: Before developing new medical facilities or adapting existing facilities in the field of stroke, it is desirable to assess not only the medical, but also the economic consequences of such facilities. Economic evaluation studies differ from other outcome studies in the way that costs are compared with effects. The purpose of this paper is to give an insight into economic evaluation studies in the field of stroke, so that these studies become easier for neurologists to understand and to apply. Summary of the Article: Crucial aspects in economic evaluation research are addressed successively, such as the techniques used and how the results can be influenced by the perspective of the study. The article also considers the inclusion of costs and consequences in economic evaluation research. At the end of this article, special issues in economic evaluation studies are presented such as discounting, sensitivity analysis, incremental analyses and ratios. Conclusions: Although neurologists have no direct responsibility for allocating scarce resources in the field of stroke, they are confronted with the results of these decisions in their everyday work. Because of this, it might be useful to have clear understanding of economic evaluation studies and their caveats.

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Development of WHO guidelines on generalized cost-effectiveness analysis

et al. 2000

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The growing use of cost-effectiveness analysis (CEA) to evaluate specific interventions is dominated by studies of prospective new interventions compared with current practice. This type of analysis does not explicitly take a sectoral perspective in which the costs and effectiveness of all possible interventions are compared, in order to select the mix that maximizes health for a given set of resource constraints. WHO guidelines on generalized CEA propose the application of CEA to a wide range of interventions to provide general information on the relative costs and health benefits of different interventions in the absence of various highly local decision constraints. This general approach will contribute to judgements on whether interventions are highly cost-effective, highly cost-ineffective, or something in between. Generalized CEAs require the evaluation of a set of interventions with respect to the counterfactual of the null set of the related interventions, i.e. the natural history of disease. Such general perceptions of relative cost-effectiveness, which do not pertain to any specific decision-maker, can be a useful reference point for evaluating the directions for enhancing allocative efficiency in a variety of settings. The proposed framework allows the identification of current allocative inefficiencies as well as opportunities presented by new interventions.

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A Comparative Review of Pharmacoeconomic Guidelines

Cited by 55 publications

References 3 publications

Cost-of-lllness Studies of Stroke

Cost-of-lllness Studies of Stroke

Economic Evaluation in Stroke Research

Development of WHO guidelines on generalized cost-effectiveness analysis

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