A Comparative Study between the Efficacy of Intratympanic Steroid Injection and Conventional Medical Treatment in Resistant Cases of Otitis Media with Effusion

Abstract

Introduction Otitis media with effusion (OME) is a multifactorial disease and the treatment options for it are limited and controversial. The aim of the present study was to compare the efficacy of intratympanic steroid injection and conventional medical treatment in resistant cases of OME with hearing loss. Materials and Methods A comparative study was conducted among 20 patients of OME with hearing loss, resistant to conventional medical treatment between December 2019 to November 2020. ‘Intratympanic dexamethasone injection’ (ITDI) was given every week for 3 consecutive weeks to one group and the other group continued to receive medical treatment. Hearing was assessed by performing pure tone audiogram before every ITDI and also at 12 weeks follow up after completion of treatment. Results Hearing improvement was found to be better in the group which received ITDI (Mean AC-PTA hearing gain = 22.88 dB) than the group where conventional medical treatment was continued (Mean AC-PTA hearing gain = 6.83 dB). Conclusion Intratympanic dexamethasone injection has significantly better outcome in term of improvement of hearing loss in resistant cases of OME than conventional medical management, and is an effective and safe therapy.

Assessment of Grommet Tube Insertion versus Myringotomy with Intratympanic Steroid Injection in Treatment of Otitis Media with Effusion

“…Secretory change of the epithelium lining the middle ear cavity, sub-epithelial edoema, and infiltration of phagocytes and lymphocytes are hallmarks of OME. The fluid in the middle ear might be the product of transudation, exudation, or active secretion by the epithelial cells that line the cavity (2) . In children, otitis media with effusion is the most common cause of hearing loss.…”

“…In addition to antibiotic therapy, steroid injections using a tympanostomy tube or intratympanic dexamethasone (ITD) were found to be more successful in the decrease of granulation tissue (2) . This research purpose was to compare the efficacy of myringotomy with intratympanic dexamethasone injection versus grommet tube insertion in treatment of OME.…”

Silent Secretory Otitis Media in Cases with Adenoid Hypertrophy

“…This therapy is not only very effective but safe as well. 10 The main aim was to detect the incidence of silent cases of SOM in patients presenting with adenoidal hypertrophy. Therefore, early therapy can be started to avoid all potential complications.…”