“…Efinaconazole (Sigma-Aldrich Co., LLC., St. Louis, MO, USA) and luliconazole (Toronto Research Chemicals, Toronto, ON, Canada) were used for the minimum effective concentration (MEC) test. Furthermore, to evaluate the therapeutic efficacy in guinea pig tinea unguium models, we used efinaconazole 10% solution (Kaken Pharmaceutical, Co., Ltd., Tokyo, Japan) prescribed clinically in Asia and North America, including Japan [10], and luliconazole 5% solution (Sato Pharmaceutical Co., Ltd., Tokyo, Japan) prescribed clinically in Japan for human onychomycosis treatment [10].…”