A comparative study for the short-term effects of targeted high-intensity UVB and narrow-band UVB in the treatment of vitiligo

Zhang, Min; Ma, Wen-Ya

doi:10.3892/etm.2017.4381

Cited by 4 publications

(3 citation statements)

References 23 publications

(27 reference statements)

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“…e treatment of vitiligo is a long process and it is impossible to have only one treatment. erefore, the information of the vitiligo patient and the "prescription" that is the treatment plan or custom treatment plan must be preserved completely [9,10]. After each treatment is over, the next treatment can continue with the last treatment time, the number of treatments, and other data.…”

Section: (2) Analysis and Design Of Data Storage And Query Functionmentioning

confidence: 99%

Design and Implementation of a Heating Treatment System for Vitiligo Skin Disease Based on Medical Ultrasound

Gao

Tian

Lyu

et al. 2021

Journal of Healthcare Engineering

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Vitiligo is relatively common clinically. It is an acquired and persistent skin and mucosal pigment depigmentation disease. As a noninvasive and nonradioactive treatment, high-energy ultrasound has been applied to skin diseases of vitiligo. Treatment achieved good clinical results. This article analyzes the structure of the original medical ultrasound system for vitiligo and finds the deficiencies and missing components of the system. On the basis of the original design scheme, a new structural scheme was designed, which solved the shortcomings of the original system and added missing parts. Subsequently, according to actual application requirements and specific component performance, the schematic design, including audio and video input, output and storage, DDR3, Ethernet, and the design of key circuits, such as power supply modules, are specifically introduced. Later, in the PCB design, the contents including stacking, layout, routing, and simulation of key signals were introduced in detail. The design includes a probe excitation signal generation module, excitation signal parameter control module, high voltage and temperature monitoring module, and corresponding power conversion module. This paper is mainly to develop a vitiligo skin disease heating treatment array system based on the principle of both cost and performance. This paper is based on the nonrigid registration algorithm of the FFD model and HPV interpolation and the nonrigid registration algorithm combining shape information and SIFT method. In the focused ultrasound treatment system, the image-guided positioning and monitoring functions are realized. Studies have shown that when the peak voltage of the transmitter circuit is 55 V, the sound power is 0.28 W. It can be seen that the transmitting circuit system designed in this article is a relatively stable and reliable system, which is suitable for the ultrasound treatment of vitiligo skin diseases.

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Section: (2) Analysis and Design Of Data Storage And Query Functionmentioning

confidence: 99%

Design and Implementation of a Heating Treatment System for Vitiligo Skin Disease Based on Medical Ultrasound

Gao

Tian

Lyu

et al. 2021

Journal of Healthcare Engineering

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“…Another study by Zhang et al. compared targeted high‐intensity UVB with NB‐UVB and found that targeted high‐intensity UVB was more effective overall but still did not produce significant improvement in acral lesions 24 . Similar poor response rates were observed in a study by Dong et al.…”

Section: Discussionmentioning

confidence: 58%

“…4 Another study by Zhang et al compared targeted high-intensity UVB with NB-UVB and found that targeted high-intensity UVB was more effective overall but still did not produce significant improvement in acral lesions. 24 The paucity of dermal stem cells at acral sites can be suggested as a potential factor contributing to the absence of pigmentation in these areas. 27 Failure of migration of melanocytes along outer root sheath to epidermis and scarcity of pilo-sebaceous units in hands and feet can also play a role in treatment resistance of acral vitiligo.…”

Section: Discussionmentioning

confidence: 99%

Whole‐body and targeted narrowband ultraviolet B phototherapy effectively stabilize acral vitiligo with negligible repigmentation beyond wrists and ankles: Results from a split‐body randomized controlled trial

Thind,

Vinay,

Mehta

et al. 2024

Photoderm Photoimm Photomed

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BackgroundNarrowband ultraviolet B (NB‐UVB) phototherapy promotes stability and repigmentation in vitiligo. No studies have compared targeted NB‐UVB with whole‐body NB‐UVB in treatment of acral vitiligo.ObjectivesThis randomized split‐body study compared whole‐body NB‐UVB with targeted NB‐UVB in inducing stability and repigmentation in acral vitiligo.MethodsThirty‐two patients with bilaterally symmetrical acral vitiligo lesions (distal to elbows and knees) were recruited. Patients received whole‐body NB‐UVB treatment, with one hand and one foot shielded until elbow and knee, followed by targeted NB‐UVB treatment on the shielded side. Patients were assessed at 4‐week intervals for 24 weeks using Vitiligo Disease Activity (VIDA) score, Vitiligo Skin Activity Score (VSAS), Vitiligo Area Scoring Index (determined through fingertip method, using the method to calculate facial‐VASI) and degree of repigmentation.ResultsAfter 12 weeks, 87.5% of patients achieved a VIDA score of 3, with none having active disease at 24 weeks. Over 50% repigmentation was observed in 42.2% and 37.5% of limbs in whole‐body and targeted groups, respectively (p = .95). No improvement in F‐VASI scores of hands and feet (distal to wrist and ankles) was noted with either modality over the 24‐week period.ConclusionOur study showed comparable repigmentation rates between whole‐body and targeted NB‐UVB groups. Limited effectiveness of phototherapy in repigmentation of hands and feet underscores an important therapeutic gap.

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The efficacy of fractional carbon dioxide laser combined with narrow-band ultraviolet B phototherapy for non-segmental vitiligo: a systematic review and meta-analysis

Kim

Lee

et al. 2020

Lasers Med Sci

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A comparative study for the short-term effects of targeted high-intensity UVB and narrow-band UVB in the treatment of vitiligo

Cited by 4 publications

References 23 publications

Design and Implementation of a Heating Treatment System for Vitiligo Skin Disease Based on Medical Ultrasound

Design and Implementation of a Heating Treatment System for Vitiligo Skin Disease Based on Medical Ultrasound

Whole‐body and targeted narrowband ultraviolet B phototherapy effectively stabilize acral vitiligo with negligible repigmentation beyond wrists and ankles: Results from a split‐body randomized controlled trial

The efficacy of fractional carbon dioxide laser combined with narrow-band ultraviolet B phototherapy for non-segmental vitiligo: a systematic review and meta-analysis

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