A comparative study of chemically induced DNA damage in isolated human and rat testicular cells

The protective effect of N-acetylcysteine against acrylamide toxicity in liver and small and large intestine tissues

“…Studies in which acrylamide was added to the cell culture medium, the oxidant parameters increased and cell damage appeared. These fi ndings support our study (55,56,(61)(62)(63).…”

“…These results show that acrylamide causes a signifi cant decrease in antioxidant parameters. Acrylamide especially decreases the GSH and GST activity levels of cells, spoils the oxidant/antioxidant balance against the oxidants and thus leads to oxidative damage in cells (1,14,(50)(51)(52)(55)(56)(57)(58).…”

A study towards release dynamics of thiram fungicide from starch–alginate beads to control environmental and health hazards

“…The disulfide group present in thiram has been reported to cause cytotoxicity due to the oxidation of -SH groups of cellular proteins, peptides and cofactors [16]. Thiram is also known as an inducer of allergic contact dermatitis and skin lesions including hand eczema or dermatitis have been often recognized among exposed workers [17][18][19]. Thiram has also been reported to have adverse effects on hepatic system [20], the reproductive system [21,17,18], and on the developmental processes [19].…”

In vitro release dynamics of thiram fungicide from starch and poly(methacrylic acid)-based hydrogels

“…It has been reported to have adverse effects on hepatic system [33], the reproductive system [34][35][36], and on the developmental processes [37]. Because of the wide range of uses of thiram and its toxic effects, there is concern about its potential effects not only on general population from dietary exposure to residues left on food crops, but also potential occupational health risks to workers who handle and often come in contact with this chemical.…”