A Comparative Study of Chest Radiographic Features Between Hiv Seropositive and Hiv Seronegative Patients of Pulmonary Tuberculosis

Abstract

Chest radiographic appearance of pulmonary tuberculosis (TB) in Human Immunodeficiency Virus (HIV) positive patients was reviewed. A study group of SO HIV +ve cases and a control group of 100 HIV ave cases were analysed. The chest radiographs of HIV seropositive group showed slgnlOcantly higher Incidence of thoracic lymphadenopathy (36% vs 8%, P<.OOI), pleural effusion (28% vs 10%, P<.OI) and miliary pattern (12% vs 2%, P<.05) as compared to the seronegative group. Cavitation was less common in the seropositive group (8% vs 35%, P<.OOI) than the seronegative group. Upper zone involvement was slgnlOcantly less common in the study group (38% vs 77%, P<.OOI) as compared to the control group. MJAFI 2002; 58: 05-08

Radiological manifestations of Pulmonary Tuberculosis in HIV Sero-Positive adult patients

“…The most common radiological pattern seen in this study was infiltrates in both HIV Sero-Positive as well as HIV Sero-Negative groups which is similar to other study. [11][12][13][14][15] Cavitary patterns were observed more in HIV Sero-Negative group than to HIV Sero-Positive individuals ( which was irrespective of sputum for AFB status) and also statistically significant like other study. [12,14] For the formation of cavity on lung parenchyma requires good delayed type of hypersensitivity response and as well as good cell mediated immunity which is lacking in HIV Sero-positive individuals.…”

“…[11][12][13][14][15] Cavitary patterns were observed more in HIV Sero-Negative group than to HIV Sero-Positive individuals ( which was irrespective of sputum for AFB status) and also statistically significant like other study. [12,14] For the formation of cavity on lung parenchyma requires good delayed type of hypersensitivity response and as well as good cell mediated immunity which is lacking in HIV Sero-positive individuals. However this is in contrast to studies by Nwonwu et al in Nigeria in which the frequency of Cavitary lesions was more common in the HIV sero-positive group.…”

“…[16] Hilar lymphadenopathy was seen only in HIV Sero-Positive patients as similar to finding seen in other study. [12,14] Fibrosis was not seen in any of cases in the HIV Sero-Positive study group due to poor cellular inflammatory response. Unilateral Pleural effusion was observed in both groups without statistically significance which is similar to Nwonwu Section: Pulmonary Medicine et al but dissimilar to studies where the incidence of pleural effusion was significantly more common in the HIV Sero-Positive group.…”

Lymphoreticular Involvement in Human Immunodeficiency Virus Infection

“…Asymmetrical involvement of lymph nodes (other than cervical, axillary and inguinal) and involvement of retroperitoneal and hilar lymph nodes is associated with significantly higher chance of developing AIDS. Debnath et al [10], reported a higher incidence of thoracic lymphadenopathy in HIV-positive patients as compared to HIV-negative controls.…”

A Cross Sectional Study for Clinical Marker of Opport I Nistic Infection in Patients With Immunodeficiency Virus Infection

“…[9] Asymmetrical involvement of lymph nodes (Other than cervical, axillary and inguinal) and involvement of retroperitoneal and hilar lymph nodes is associated with significantly higher chance of developing AIDS. Debnath et al [10] reported a higher incidence of thoracic lymphadenopathy in HIV-positive patients as compared to HIV-negative controls.…”