A comparative study of circulating plasma lipid components and superoxide dismutase activity in pre and postmenopausal women

Chaudhari, Priyanka; Kushwaha, Rajeev Singh; Raturi, Shikha; Naithani, Swati; Sailwal, Shivani; Sharma, Sumita; Bhat, K. Shankar; Masood, Tariq; Singh, Raj Kumar

doi:10.18203/2320-6012.ijrms20162698

Cited by 1 publication

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“…The changes in the concentration of HDL-C and HDL particles composition after menopause have been subject of controversy. The decrease HDL-C in postmenopausal T2DM women (p<0.001) in present investigation is in accordance with the findings of Chaudhari et al [15].…”

Section: Discussionsupporting

confidence: 93%

Status of vitamin-D in relation to glycemic indices and lipid profile in postmenopausal women with type 2 diabetes mellitus: a case controlled study in Riyadh, KSA

Abudawood¹,

Aljaser²,

Tabassum³

et al. 2018

Biomed Res

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Abnormal vitamin D level and glucose homeostasis are two most chronic medical conditions leading to cardiovascular disease following menopause transition in females. Low levels of vitamin D could be associated with elevated risk of type 2 diabetes mellitus (T2DM). The aim of the present study was to evaluate and compare vitamin D status in relation to glycemic indices, metabolic parameters between pre and postmenopausal women with T2DM. Levels of fasting blood glucose, HbA1C, lipid profile and vitamin D were measured in pre and postmenopausal T2DM women and analysed by SPSS software. Levels of HbA1C, FBG, TC, Tg, LDL-C and obesity parameters like BMI and visceral fat increased significantly (p<0.001) whereas serum levels of HDL-C and vitamin D decreased significantly in postmenopausal T2DM women compared to premenopausal group. Vitamin D was negatively correlated with age, HbA1C, LDL-C at p<0.05. Decreased levels of vitamin D exhibited strong negative correlation with metabolic or obesity factors like BMI and waist circumference. The present investigation unravels the relationship between vitamin D and cholesterol and it was found that HDL-C although decreased with menopause, there was no significant association between HDL-C and decreased vitamin D in postmenopausal T2DM females. Results from this study suggests that hypovitaminosis D accompanied with dyslipidimia, increased BMI and obesity increases the risk factors for cardiovascular diseases in postmenopausal women with T2DM.

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Section: Discussionsupporting

confidence: 93%