A Comparative Study of Plastic (Polypropylene) and Glass Syringes in Blood-Gas Analysis

Accuracy and clinical performance of a continuous intra-arterial blood-gas monitoring system during thoracoscopic surgery

“…Comparison of the two methods was not the object of this study. Comparing PT7 and laboratory blood-gas analysis results is difficult because laboratory blood-gas analysis measurement is fraught with a variety of problems: samples for blood-gas analysis may easily be handled incorrectly by sample dilution, excess heparinized saline, 20 21 delays in analysis with the sample being stored at room temperature, 20 22 oxygen consumption from metabolism by leucocytes and other cells contained in the sample, 23 diffusion of gases through the plastic wall of syringes [24][25][26] and pressure of air bubbles in the samples, 22 26 27 particularly during transport. 28 In addition, the accuracy and variability of laboratory blood-gas analysers are applied in a recent evaluation of blood-gas analysers 29 : in the PO 2 range of 4-20 kPa and PCO 2 range of 2.7-10.6 kPa, respectively, 95% of measurements should be within Ϯ7.5% or Ϯ0.6 kPa of a reference; for PO 2 920 kPa and PCO 2 910.6 kPa, respectively, 95% of measurements should be within Ϯ12.5% of a reference; pH accuracy cannot be tested because there is no reference method.…”

Interpretation of Blood Gas Measurements

“…Nucleated white blood cells and platelets consume oxygen and produce carbon dioxide. 5,6 Dilution of the blood sample by anticoagulant will also change the measured values. Important changes in the measured blood gas values may occur with room temperature storage times of as little as 10 minutes.…”

Glass syringes are better than plastic for preserving arterial blood gas for oxygen partial pressure determination: an explanation based on nanomaterial composition

“…The effect of syringe material on collected blood in general clinical chemistry has also been reported, including the diffusion of chemicals across the tube (Hilty et al 1969; Scott et al 1971). For blood gas analysis, the classical method requires a glass syringe; however, the new plastic syringes have been developed to address the increasing problems of blood-borne transmitted diseases (Evers et al 1972). …”