A comparative study of UHPLC/Orbitrap MS metabolomics profiles and biological properties of Asphodeline taurica from Bulgaria and Turkey

Lazarova, Irına; Zengin, Gökhan; Gevrenova, Reneta; Nedialkov, Paraskev; Aneva, Ina; Aumeeruddy, Muhammad Zakariyyah; Mahomoodally, Mohamad Fawzi

doi:10.1016/j.jpba.2019.02.008

Cited by 8 publications

(4 citation statements)

References 24 publications

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“…Studies are focused on natural antioxidants in order to prevent the negative effects of the synthetic antioxidants in human life. It has been proved that compounds such as polyphenols, anthraquinones, phenolic terpenes and flavonoids are responsible for the antioxidant activity of plants (Uysal et al, 2018;Zengin et al, 2018a, b;Lazarova et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Usage of encapsulated Hypericum scabrum in Ayran and determination of antioxidant, phenolic and sensory properties

Seyrekoğlu

Temiz

Eser

et al. 2022

International Journal of Science Letters

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Hypericum scabrum (HS) widely used in traditional medicine due to its bioactive compounds was extracted by using ethanol-water (3:7, v/v). The extract was encapsulated with maltodextrin and gum arabic in a spray dryer in order to protect the phenolic compounds in its structure. Different amounts of microcapsules were added to our traditional drink, i.e. ayran (drinking yoghurt). The total phenolic content (TPC) and DPPH radical scavenging activity of the microcapsules in extract of HS and ayran samples were determined. The amount of total phenolic compounds in the microcapsule provided a superior effect than the extract. The ayran samples were supplemented with 2%, 3%, 4%, 5% and 6% of Hypericum scabrum microcapsules and it is observed that total phenolic content and DPPH radical scavenging activity indicated an increase with concentration. TPC and DPPH activity were determined as 268.86 mg GAE100 mL -1 and 78.05% for 6% supplemented samples. As a result of the sensory analysis, ayran samples supplemented with 4% of HS microcapsule gained the highest scores by the panelists and received more appreciation than the control group. It is concluded that HS4 (ayran produced by 4% HS supplemented microcapsule) sample was determined as the best sample according to the sensory analyses while the HS6 (ayran produced by 6% HS supplemented microcapsule) sample had the highest value in terms of DPPH scavenging activity and TPC results. The overall results of the present study revealed that 4% HS supplemented ayran can be produced with its enhanced health beneficial and desirable properties.

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Section: Introductionmentioning

confidence: 99%

Usage of encapsulated Hypericum scabrum in Ayran and determination of antioxidant, phenolic and sensory properties

Seyrekoğlu

Temiz

Eser

et al. 2022

International Journal of Science Letters

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“…Peaks at m/z 375.1444 and 519.1858 showed the presence of two lignans, cycloolivil (43) and pinoresinol-4-O-glucoside (50). They were identified only in decoctions of F. vulgare.…”

Section: Identification Of Metabolites In F Vulgare Extracts By Lc-esi/ltqorbitrap/ms and Lc-esi-ltqorbitrap/ms/ms Analysismentioning

confidence: 99%

“…Compounds 38 and 51 were putatively identified as gingerol and lusitanicoside, respectively; lusitanicoside was characterized on the basis of the presence of the fragment ion at m/z 133.06, due to the neutral loss of rutinoside moiety [46,50].…”

Section: Identification Of Metabolites In F Vulgare Extracts By Lc-esi/ltqorbitrap/ms and Lc-esi-ltqorbitrap/ms/ms Analysismentioning

confidence: 99%

LC-ESI/LTQOrbitrap/MS Metabolomic Analysis of Fennel Waste (Foeniculum vulgare Mill.) as a Byproduct Rich in Bioactive Compounds

Crescenzi

D’Urso

Piacente

et al. 2021

Foods

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Food industries produce a high amount of waste every year. These wastes represent a source of bioactive compounds to be used to produce cosmetic and nutraceutical products. In this study, the possibility to retrain food waste as a potential source of bioactive metabolites is evaluated. In particular, metabolite profiles of different parts (bulb, leaves, stems and little stems) of fennel waste were investigated by liquid chromatography coupled with mass spectrometry (LC-ESI/LTQ Orbitrap MS). To discriminate the different plant parts, a Multivariate Data Analysis approach was developed. Metabolomic analysis allowed the identification of different metabolites mainly belonging to hydroxycinnamic acid derivatives, flavonoid glycosides, flavonoid aglycons, phenolic acids, iridoid derivatives and lignans. The identification of compounds was based on retention times, accurate mass measurements, MS/MS data, exploration on specific metabolites database and comparison with data reported in the literature for F. vulgare. Moreover, the presence of different oxylipins was relieved; these metabolites for the first time were identified in fennel. Most of the metabolites identified in F. vulgare possess anti-inflammatory, antioxidant and/or immunomodulatory properties. Considering that polyphenols are described to possess antioxidant activity, spectrophotometric tests were performed to evaluate the antioxidant activity of each part of the fennel.

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“…Başta antrokinonlar, fenolik asitler ve flavonoidler olmak üzere çeşitli bileşikler bu çalışmalarda rapor edilmiştir [11,[18][19][20][21][22][23][24]. Yine yapılan çeşitli çalışmalarda Asphodeline üyelerinin antioksidan, antimikrobiyal, antikanser ve karaciğer koruyucu özellikler gibi biyolojik aktiviteleri de belirlenmiştir [11,[19][20][21][22][23][24][25][26][27][28]. Bununla birlikte cins üyelerinin kimyasal profilleri ve biyolojik aktiviteleri üzerine yapılan çalışmalar halen yeterli seviyede değildir.…”

Section: Introductionunclassified

A Study on Antioxidant and Enzyme Inhibitory Properties of Extracts from Different Parts of Asphodeline baytopae (Xanthorhoeaceae)

Zengin

Aktümsek

2021

Türk Doğa Ve Fen Dergisi

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Öz: Asphodeline Reichb. cinsi gıda ve ilaç kaynağı olarak büyük bir ilgiye sahiptir. Bu çalışmada, Asphodeline baytopiae Tuzlaci''nin (Xanthorhoeaceae) farklı kısımlarından (kök, gövde, yaprak ve tohum) elde edilen farklı çözücü ekstraktlarının (aseton, metanol ve su) biyolojik aktiviteleri belirlenmiştir. Biyolojik özellikleri için; antioksidan ve enzim inhibitör etkileri ortaya konulmuştur. Serbest radikal (DPPH ve ABTS), indirgeme gücü (CUPRAC ve FRAP), metal şelatlama ve fosfomolibdat testlerini içeren farklı antioksidan test sistemleri kullanılmıştır. Ayrıca, enzim inhibitör etkiler kolinesterazlar (AChE ve BChE), tirozinaz, α-amilaz ve α-glukozidaz'a karşı araştırılmıştır. Bunlara ek olarak, her bir ekstraktın toplam fenolik ve flavonoid içerikleri de belirlenmiştir. Gövde-metanol ekstraktının en yüksek toplam fenolik (73.57 mg GAE/g ekstrakt) ve flavonoid (75.04 mg RE/g ekstrakt) içeriğine sahip olduğu görülmüştür. Genel olarak, gövde ekstrakları; yaprak, kök ve tohum ile kıyaslandığında güçlü antioksidan yetenekler sergilemektedir. Kolinesteraz inhibisyon testlerinde, aseton ve metanol ekstraktlar inhibitör etkiler gösterirken, su ekstraklarının aktif olmadığı gözlenmiştir. Tirozinaz inhibitör etkileri 4.83 ile 74.64 mg KAE/g ekstrakt arasında değişmektedir. α-Amilaz ve α-glukozidaz inhisyonu sırasıyla 0.22-0.77 mmol ACAE/g ekstrakt ve 3.42-4.65 mmol ACAE/g ekstrakt şeklindedir. Bu sonuçlar A. baytopiae'nin gıda ve farmasötik endüstrileri için doğal ajanların değerli bir kaynağı olarak düşünülebileceğini önermektedir.

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A comparative study of UHPLC/Orbitrap MS metabolomics profiles and biological properties of Asphodeline taurica from Bulgaria and Turkey

Cited by 8 publications

References 24 publications

Usage of encapsulated Hypericum scabrum in Ayran and determination of antioxidant, phenolic and sensory properties

Usage of encapsulated Hypericum scabrum in Ayran and determination of antioxidant, phenolic and sensory properties

LC-ESI/LTQOrbitrap/MS Metabolomic Analysis of Fennel Waste (Foeniculum vulgare Mill.) as a Byproduct Rich in Bioactive Compounds

A Study on Antioxidant and Enzyme Inhibitory Properties of Extracts from Different Parts of Asphodeline baytopae (Xanthorhoeaceae)

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