A comparative study on synthesis of some novel α,β-unsaturated carbonyl derivatives and their antioxidant potential

Ahmad, Mohammed Rayees; Khan, Mohammed Haseebur Rahman; Sastry, V. Girija; Bano, Nasreen; Anwar, S. Y.; Prasad, Y. Rajendra

doi:10.5155/eurjchem.3.2.186-190.554

Cited by 6 publications

(1 citation statement)

References 21 publications

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“…It has the general structural formula as shown in Figure 1. Chalcone may be called some names as benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, α-phenyl-β-benzoylethylene, and others [3,4]. Many of chalcones possess interesting pharmacological properties such as antibacterial [5], antifungal [6], antiviral [7], anti-HIV activity [8], 5-lipoxygenase inhibitor [9], anticancer [10][11][12], cytotoxic activity [13], antimalarial [14], antiulcer [15], antileishmanial [16], and anti-inflammatory [17].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, reactions, and applications of chalcones: A review

Morsy

Hassan

2022

Eur J Chem

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Considering the essential biological and medicinal properties of chalcones, the synthesis of these compounds has attracted the interest of medicinal and organic chemists. This review aims to describe the different strategies developed so far for the synthesis of chalcones and their applications. After a brief introduction of the chalcones and their biological activities, different synthetic approaches such as chemical and other methods are described and organized on the basis of the catalysts and the other reagents employed in the syntheses. Some of the reactions have been applied successfully to the synthesis of biologically important compounds. Moreover, the biological and pharmacological activities of chalcones have been shown.

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Section: Introductionmentioning

confidence: 99%

Synthesis, reactions, and applications of chalcones: A review

Morsy

Hassan

2022

Eur J Chem

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Five-Membered Ring Systems

Biehl¹

2013

Progress in Heterocyclic Chemistry

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The solid-state emmissive chalcone (2E)-1-(5-chlorothiophen-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

et al. 2015

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Orange rectangular blocks suitable for X-ray diffraction analysis were obtained for the previously reported [Ahmad & Bano (2011). Int. J. ChemTech Res. 3, 1470-1478] title chalcone, C15H14ClNOS. This solid-emissive chalcone exhibits a planar structure and the bond parameters are compared with related compounds already described in the literature. The determination of the structure of this chalcone is quite relevant because it will play an important role in theoretical calculations to investigate potential two-photon absorption processes and could also be useful for studying the interaction of such compounds with a biological target.

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A comparative study on synthesis of some novel α,β-unsaturated carbonyl derivatives and their antioxidant potential

Cited by 6 publications

References 21 publications

Synthesis, reactions, and applications of chalcones: A review

Synthesis, reactions, and applications of chalcones: A review

Five-Membered Ring Systems

The solid-state emmissive chalcone (2E)-1-(5-chlorothiophen-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

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