Loess is a kind of soil that experiences a long period of deposition, and it is relatively stable under natural conditions. However, in the process of engineering construction in loess areas, the original soil structures of the loess are destroyed, inducing changes in the composition and water content in the loess. These changes may cause different environmental and engineering geologic problems. To reveal the engineering properties of disturbed losses in the Chinese Loess Plateau, the physical properties of 135 groups of disturbed loess samples in Yan’an City were analyzed statistically, and the compression properties of loess with different moisture contents and dry densities were studied by high-pressure consolidation experiments. We elucidate the compressive deformation law for perturbed solids at different moisture contents and dry densities. The experimental results show that the water content rate for the best compaction performance of the disturbed loess is 16%. The compressive deformation coefficient generally decreases with increasing dry density and water content. However, when the soil moisture is low, a small amount of water and salt is concentrated in the contact position of the powder, and the soluble salt is condensed into cement. The molecular forces between particles and the bonding forces of bound water and capillary water are larger. The soil forms a porous structure with coarse grains as the main skeleton, and the cement bonding strength is strong at the contact points of the coarse grains. As a result, the loess shows high intensity at low-water content. This results in a compression-deformation coefficient that increases with dryness density in the small load range.