A Comparative Study to Analyze the HBA1C and LIPID Profile in Type 2 Diabetic Patients with and without Diabetic Complications

Hussain, Akhtar; Rehman, M Saqib Ur; Kapoor, Aneel; Mengal, Muhammad Ibrahim; Kumar, Narindar; Hassan, Hanozia

doi:10.53350/pjmhs22165492

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“…Hazari et al found that individuals with type II DM and DPN have prominent changes in their foot kinematics and kinetics, putting them at a higher risk for foot ulceration with underlying neuropathy and biomechanical manifestations 15 . A higher degree of functional impairment, a reduction in health-related quality of life, and difficulties with everyday tasks are all linked to painful DPN 16 , 17 .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of peripheral neuropathy, amputation, and quality of life in patients with diabetes mellitus

Perveen,

Ahsan,

Rameen Shahzad

et al. 2024

Sci Rep

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Peripheral neuropathy and amputation are common complications of diabetes mellitus (DM) that significantly impact the quality of life of the affected individuals. This study aims to investigate the prevalence of peripheral neuropathy, the level of amputation, and the quality of life in patients with DM. This cross-sectional study was conducted after approval of the synopsis involving 225 diagnosed patients with DM on pre-defined eligibility criteria, selected from public sector OPDs, specialized diabetes centres, and centres manufacturing orthotics and prosthetics. Data were collected through interviews, observations, and the administration of the Michigan Neuropathy Screening Instrument and the Asian Diabetes Quality of Life Questionnaire. The level of amputation was recorded for each participant. Data was entered into SPSS, and results were synthesized. Pearson correlation is applied to find an association between gender and the quality of life of the participants, while P ≤ 0.05 will be considered significant. The prevalence of peripheral neuropathy in a sample of 225, based on a self-administered questionnaire, was (44.4%), and in terms of foot examination was (51.1%). As people progressed in age, the prevalence increased to 20.0% in patients above 60 years and 8.9% in ≤ 35 years of age. The majority of participants (56.0%) have had DM for less than five years. Females were 57.8% of the study population, while 97.8% of participants had type II DM. Below-knee amputation of the right limb was observed in 22(9.8%) of the participants. The QoL was poor in the majority of the participants (96.9%) patients with DM (P = 0.638 and T = -0.471). This cross-sectional study highlights a high prevalence of peripheral neuropathy and amputation and poor QoL in patients with diabetic mellitus.

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Section: Introductionmentioning

confidence: 99%