A comparative trial of liver biopsy needles.

Bateson, M C; Hopwood, D; Duguid, H L; Bouchier, I. A. D.

doi:10.1136/jcp.33.2.131

Cited by 38 publications

(1 citation statement)

References 6 publications

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“…8 Although simple end-cutting systems with a beveled 45°convex tip have already been developed in the past, the fragmentation rate of these systems was significantly higher than with side-notch systems, but yielding larger specimen volumes. 9 While the end-cut needle has also been shown to be safe for biopsy of other organs like lung or liver, 6 the adequacy of the specimen using the full-core and sidenotch design for those organs has not been examined yet. Therefore, the objective of this prospective study was to compare the diagnostic valence of the specimen of a fullcore, end-cut device compared with a side-notch device in a randomized and controlled manner.…”

Section: Discussionmentioning

confidence: 99%

<p>Full-Core Biopsy Systems Take Larger Liver Tissue Samples with Lower Fragmentation Rates Than Conventional Side-Notch Systems: A Randomized Trial</p>

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Utpatel

Verloh

et al. 2020

CMAR

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Background: The aim of this study was to compare the histopathological quality and physical features of the specimen of a full-core end-cut biopsy system with that of the standard side-notch system for liver biopsies. Methods: A full-core end-cut 16G biopsy device and a standard side-notch 16G needle were used to take biopsies of unclear liver lesions. Patients were randomized in two groups of 16 patients each. The primary endpoint of this prospective study was the core length measured using a dedicated microscope imaging software. Secondary endpoints were the quality of the specimen rated by an independent pathologist unaware of the device (scale from 1 to 5; with 1 as best and 5 as worst), the core diameter (determined by the microscopic imaging software) and presence of fragmentation (evaluated by the pathologist). Results: For the full-core (FC) and side-notch (SN) groups, the mean core length was similar with 13,599 μm and 11,570 μm (p=0.131), respectively. The quality of the specimen was significantly better in the FC-group with an average rating of 1.68 vs 2.50 (p=0.009). The fragmentation rate in the FC-group was statistically significantly lower at 2/27 (7%) than in the SN-group at 13/33 (39%) (p=0.021). The diameter in the FC-group was 1042 μm vs 930 μm in SN-group (p=0.018).

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Section: Discussionmentioning

confidence: 99%