A comparison between 2D and 3D planning of 
high-dose-rate vaginal cuff brachytherapy in patients with stage I-II endometrial cancer using cobalt-60

Hashemi, Fatemeh; Mansouri, Sepideh; Aghili, Mahdi; Esmati, Ebrahim; Babaei, Mohammad; Saeedian, Arefeh; Moalej, Sepand; Jaberi, Ramin

doi:10.5114/jcb.2021.110312

Cited by 4 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 3D planning, CTV-VC was contoured by using 5 mm strip around cylinder with narrowing or expanding the thickness based on the thickness of vagina on each CT slide or the adjacent organs. The result showed 3D planning can deliver suitable dose to the target while reduce the dose to organs at risk ( Hashemi et al, 2021 ). In term of the thickness of strip for vaginal CTV, the findings of the MRI-based IG-VBT demonstrated that the vaginal wall has a thickness of 2.16–2.24 mm ( Boonyawan et al, 2014 ).The study of vaginal wall histology demonstrated 95 % of vaginal lymphatic channels are located within 3 mm of the vaginal surface and all vaginal lymphatic channels are located within 4 mm ( Choo et al, 2005 ).…”

Section: Discussionmentioning

confidence: 99%

Preliminary results of adjuvant image-guided vaginal brachytherapy alone for early stage endometrial carcinoma

Muangwong,

Tharavichitkul,

Chakrabandhu

et al. 2024

Gynecologic Oncology Reports

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Preliminary results of adjuvant image-guided vaginal brachytherapy alone for early stage endometrial carcinoma

Muangwong,

Tharavichitkul,

Chakrabandhu

et al. 2024

Gynecologic Oncology Reports

View full text Add to dashboard Cite

“…Studies suggest that high AMH level is also protective against of endometrial cancer 8 . Endometrial cancer is often treated with total hysterectomy and bilateral salpingo‐oophorectomy (TH‐BSO) followed by adjuvant radiation therapy 9 …”

Section: Introductionmentioning

confidence: 99%

“… 8 Endometrial cancer is often treated with total hysterectomy and bilateral salpingo‐oophorectomy (TH‐BSO) followed by adjuvant radiation therapy. 9 …”

Section: Introductionmentioning

confidence: 99%

The protective effect of vitamin D on ovarian reserve and anti‐mullerian hormone in patients undergoing chemotherapy for breast cancer, a randomized phase ΙΙ clinical trial

Dastmardi,

Lashkari,

Saeedian

et al. 2024

Cancer Reports

Self Cite

View full text Add to dashboard Cite

BackgroundReduced ovarian reserve is among the crucial long‐term side effects of using chemotherapy agents in breast cancer, yielding early ovarian failure. On the other hand, vitamin D is an essential factor in protecting the follicles and an important predictive factor for successful IVF therapy.AimThe aim of this study is evaluation of vitamin D as a agent that can reduce fertility complications of chemotherapy specially in young women.MethodsBreast cancer patients undergoing chemotherapy at two cancer institutes were enrolled in this study. The case group received 1000 IU of calcitriol, and the AMH level was measured at the baseline, after chemotherapy, and six months after chemotherapy. The primary end point was improvement in the AMH level after six months of chemotherapy. the secondary endpoint was to evaluate the predictive factors of AMH level decline during chemotherapy.ResultsBetween 2018 and 2019, 18 and 15 patients were enrolled in the case and control groups, respectively. The mean AMH level (ngr/ml) of the patients in the case and control group were 3.16 and 2.37 ng/mL, respectively (p‐value = .16). These levels were 0.387 and 0.19 after six months (p‐value = .38). The AMH rise immediately after chemotherapy cycles to six months after chemotherapy, in the case and control groups were 0.86 and 0.44 ng/mL, respectively, which was slightly higher in the case group but not statistically significant between two groups (p‐value = .054).ConclusionDespite a minimal rise in the AMH level after six months of chemotherapy, the study could not demonstrate any protective effect of vitamin D on patients' ovarian reserve undergoing chemotherapy for breast cancer. Further larger studies are needed to evaluate the effect of vitamin D supplements on ovarian reserve beside optimal dose and duration.

show abstract

Jinekolojik endokaviter brakiterapi uygulamalarında bilgisayarlı planlama ve TLD dozimetrisi ölçümlerinin karşılaştırılması

Olacak,

Özsaran

2024

Ege Tıp Dergisi

View full text Add to dashboard Cite

Amaç: Opere/inopere serviks ve endometrium kanserli hastaların endokaviter brakiterapi tedavisinde rektum ve mesane dozlarının dozimetrik değerlendirilmesidir. Gereç ve Yöntem:10 inopere, 12 opere serviks ve endometrium kanserli hastaların endokaviter brakiterapi tedavilerinde rektumdaki dozları ölçmek için, thermolüminisans dozimetre (TLD) içeren rektal prob yerleştirildi. Mesane dozlarını belirlemek için mesane boynuna foley sonda (balon) ve tabanına bir zincir yerleştirildi. Hastaların simülatörde çekilen radyografileri üzerinde aplikatör noktaları, vajen, mesane ve rektum noktaları belirlenip brakiterapi tedavi planlama sisteminde doz dağılımları hesaplatıldı. Rektumda 4 noktada hesaplanan ve TLD ile ölçülen dozlar yüzde fark olarak karşılaştırıldı. Mesane boynundaki doz, tabanındaki en yüksek doz ile istatistiksel olarak karşılaştırıldı. Bulgular: Rektum için, opere ve inopere hastalarda iki teknik arasındaki farklar; sırasıyla, maksimum %17,68 ve %17,96, minimum %0,38 ve %0,20, ortalama R1: %5,62, R2: %4,22, R3: %5,96, R4: %7,58 ve R1: %6,73, R2: %4,36, R3: %4,34, R4: %7,53 olarak belirlendi. Mesane boynu ile tabanındaki maksimum doz noktası arasındaki fark opere hastalarda anlamlı (p=0,0037) iken, inopere hastalarda anlamsız bulundu (p=0,3863). Sonuç: Rektumda hesaplanan ile ölçülen dozlar arasındaki fark klinik açıdan önemli değildir. Rektal komplikasyonlar için dozlar birçok noktada belirlenmelidir. Mesane boynunda belirlenen doz mesane komplikasyonları için yeterli değildir, mesane tabanında da dozlar belirlenmelidir.

show abstract

A comparison between 2D and 3D planning of high-dose-rate vaginal cuff brachytherapy in patients with stage I-II endometrial cancer using cobalt-60

Cited by 4 publications

References 23 publications

Preliminary results of adjuvant image-guided vaginal brachytherapy alone for early stage endometrial carcinoma

Preliminary results of adjuvant image-guided vaginal brachytherapy alone for early stage endometrial carcinoma

The protective effect of vitamin D on ovarian reserve and anti‐mullerian hormone in patients undergoing chemotherapy for breast cancer, a randomized phase ΙΙ clinical trial

Jinekolojik endokaviter brakiterapi uygulamalarında bilgisayarlı planlama ve TLD dozimetrisi ölçümlerinin karşılaştırılması

Contact Info

Product

Resources

About