A Comparison of a Spectrophotometric and the Silver Salt Titration Methods for the Determination of Theophylline in Various Pharmaceuticals*

Comer, J.P.; Hilty, W.W.

doi:10.1002/jps.3030430510

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Clinical Pharmacology and Therapeutics1

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1955

1972

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Cited by 4 publications

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“…in O.lN HCI. 3 t With the exception of 1-methylxanthine ( Cyclo Chemical), these were kindly synthesized by Dr. Herbert Nagasawa of this institution,…”

Section: Clinical Pharmacology and Therapeuticsmentioning

confidence: 99%

Pharmacokinetics of theophylline; Application to adjustment of the clinical dose of aminophylline

Jenne

Wyze

Rood

et al. 1972

Clin Pharma and Therapeutics

492

116

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“…in O.lN HCI. 3 t With the exception of 1-methylxanthine ( Cyclo Chemical), these were kindly synthesized by Dr. Herbert Nagasawa of this institution,…”

Section: Clinical Pharmacology and Therapeuticsmentioning

confidence: 99%

Pharmacokinetics of theophylline; Application to adjustment of the clinical dose of aminophylline

Jenne

Wyze

Rood

et al. 1972

Clin Pharma and Therapeutics

492

116

View full text Add to dashboard Cite

“…Acidic solutions of both alkaloids have similar maxima, but theobromine shows a considerable increase in absorption in the 220 to 254 mg range in alkaline solution (253). An ultraviolet spectrophotometric method for the determination of theophylline in pharmaceuticals has been compared with the silver salt procedure (85). The instrumental method compares well with the official procedure and avoids some errors.…”

mentioning

confidence: 99%