A Comparison of Bone Mineral Density between Caucasian, Asian and Afro-Caribbean Women

Tobias, J.H.; Cook, Derek G; Chambers, T.J.; Dalzell, Nichola

doi:10.1042/cs0870587

Cited by 99 publications

(45 citation statements)

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“…When bone size was adjusted for, BMAD values at the lumbar spine and femoral neck were actually somewhat greater for Somali than for white women. Likewise, recent studies have shown that adjustment for bone or body size reduces apparent differences in bone density between white and Asian women [31,44,[51][52][53][54][55]. However, this correction did not equilibrate bone density values among those of African heritage, as BMAD values were still significantly greater among AA than Somali women.…”

Section: Discussionmentioning

confidence: 81%

Variations in Bone Density among Persons of African Heritage

Melton¹,

Marquez

Achenbach³

et al. 2002

Osteoporos Int

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The epidemiology of bone loss in populations of African heritage is still poorly known. We compared a convenience sample of 47 African-American (AA) residents of Rochester, Minnesota (32 women, 15 men) and 66 recent immigrants from Somalia (all women) with 684 white subjects (349 women, 335 men) previously recruited from an age-stratified random sample of community residents. Areal bone mineral density (BMD, g/cm(2)) and volumetric bone mineral apparent density (BMAD, g/cm(3)) were determined for lumbar spine and proximal femur using the Hologic QDR 2000 for white subjects and the QDR 4500 for the others; the instruments were cross-calibrated from data on 20 volunteers. Lumbar spine BMD was 18% higher in AA ( p<0.001) and 4% lower in Somali ( p = 0.147) than white women. Femoral neck BMD was 27% higher in AA women but also 11% greater in Somali women (both p<0.001) compared with whites. Lumbar spine BMD was 6% higher ( p = 0.132) and femoral neck BMD 21% higher ( p<0.001) in AA than white men. No Somali men were studied. After correcting for bone size differences, both lumbar spine ( p<0.01) and femoral neck BMAD ( p<0.001) were greater for Somali than white women, but the difference between Somali and AA women persisted. Lumbar spine and femoral neck BMAD values also remained significantly greater for AA women (both p<0.001) and men ( p<0.05; p<0.001) compared with whites. Weight was associated with BMAD at both skeletal sites in all groups, but adjustment for differences in weight did not reduce the discrepancy in BMAD values between Somali and AA women or between the latter group and whites. This heterogeneity among different ethnic groups of African heritage may provide an opportunity for research to better explain race-specific differences in bone metabolism.

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Section: Discussionmentioning

confidence: 81%

Variations in Bone Density among Persons of African Heritage

Melton¹,

Marquez

Achenbach³

et al. 2002

Osteoporos Int

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“…Nevertheless, the large differences in mean UCa between the three ethnic groups (with whites excreting approximately 1.0 mmol per day more calcium in their urine than blacks or S Asians) might help explain the higher bone density of blacks 36 and why osteoporosis 37,38 and bone fractures 39,40 are more common in whites than in blacks or S Asians. Despite these differences the association of UCa with both BP and UNa was independent of ethnic origin.…”

Section: Discussionmentioning

confidence: 99%

Urinary calcium excretion, sodium intake and blood pressure in a multi-ethnic population: results of the Wandsworth Heart and Stroke Study

et al. 2001

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Background: Hypertension is associated with increased urinary calcium excretion (UCa). A high sodium intake increases both UCa and blood pressure (BP). However, it is not clear whether these effects are modified by gender or ethnic origin. Objectives: To examine the relationships between BP, urinary sodium (UNa), gender and ethnic origin with both daily and fasting UCa in a population-based study. Design and Methods: Out of 1577 individuals taking part in a cross-sectional survey, 743 were considered for the present analysis (407 women, 336 men) as they were all untreated, had provided a complete 24-h urine collection, and had all measurements of anthropometry, BP, UNa and UCa. They were 277 whites, 227 of black African origin and 239 South Asians. Comparisons were also carried out in the 690 participants who also provided 3-h fasting urine collections. Results: After adjustment for confounders including age, and gender, 24-h UCa was significantly and independently associated with ethnic origin, BP and UNa. Mean 24-h UCa was 4.62 (s.e. 0.11) mmol/d in whites,

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“…From an endocrine kinetic standpoint, while menarche or pregnancy may also affects on the BMD (Ozdemir et al 2005), we focused on the time of the menopause and climacteric in the present study. BMC and BMD have been reported to be lower in Asian than Caucasian adults (Tobias et al 1979;Walker et al 2006). These racial differences may be the result of differences in life style, such as food intake and physical exercise.…”

Section: Discussionmentioning

confidence: 99%

Accelerated Decrease in Bone Mineral Density in Women Aged 52-57 Years

Nohara

Kamei

Ohta

2006

Tohoku J. Exp. Med.

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Bone mineral density (BMD) has been known to decline in middle-aged and elderly individuals, but when this decline begins and the rate at which it occurs remain unclear. We thus undertook this study to examine the association between BMD and age by their mean values in women visiting the Shimane Institute of Health Science for medical examination. We performed dual energy X-ray absorptiometry measurement of lumbar vertebrae in 1,167 women, and of the entire skeleton in 1,038 women. The ages of subjects ranged from 30 to 70 years. We found that the mean value of whole-body and lumbar BMD changed little in the age range of 30-51 years, and any change after 58 years was a gradual decrease, unlike the sharp decrease found between 52 and 57 years of age. The effects of endocrine kinetics may be reflected in women by the decrease of bone density relative to age. In conclusion, BMD declines more rapidly in women within the age range of 52-57 years than in those 58 years and over. This regression line is considered useful in predicting BMD of whole-body skeleton and lumbar vertebrae relative to age for the prevention of osteoporosis in women.

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A Comparison of Bone Mineral Density between Caucasian, Asian and Afro-Caribbean Women

Cited by 99 publications

References 0 publications

Variations in Bone Density among Persons of African Heritage

Variations in Bone Density among Persons of African Heritage

Urinary calcium excretion, sodium intake and blood pressure in a multi-ethnic population: results of the Wandsworth Heart and Stroke Study

Accelerated Decrease in Bone Mineral Density in Women Aged 52-57 Years

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