A comparison of clinical and laboratory data on neutron therapy for locally advanced tumors

Neutron Versus Photon Radiotherapy for Local Control in Inoperable Breast Cancer

“…This may be due predominantly to tumor volumes being smaller in other series. Only Catterall et al [6] report a mean diameter (of 9.7 cm). In our neutron group the mean tumor volume was 1,097 cm 3 and mean diameter 12.8 cm.…”

“…However, this regimen did not protect against late normal tissue damage. Catterall et al reported a complete response rate of 95% and do recommend the use of neutrons as a modality for breast cancer control [6,7].…”

“…In countries with limited resources, such as South Africa, breast cancer is often diagnosed late [9,21]; so the treatment of inoperable, advanced local disease is of particular relevance. Promising results have previously been reported in the treatment of this condition with neutron therapy [5][6][7]26], although the value remains controversial [13].…”