A comparison of corneal sensitivity between brachycephalic and Domestic Short‐haired cats

Blocker, Tiffany; Woerdt, Alexandra van der

doi:10.1046/j.1463-5224.2001.00189.x

Cited by 73 publications

(108 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, this information is similar to those reported by Blocker and Van Der Woerdt (2001) in cats and by Brooks et al (2000) in horses. Barret et al (1991) and Herring et al (2005) observed that dolichocephalic dogs exhibit esthesiometry values of 1.75cm, similar to the results obtained in this study (1.7cm).…”

Section: Arqsupporting

confidence: 90%

Effects of the Ottonia martiana Miq. (Piperaceae) extract on dog's ocular surface

Lisbão

Correa

Ortiz

et al. 2012

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

The anesthetics effects of aqueous extract of Ottonia martiana leaves were studied on the ocular surface of healthy beagle dogs. The dogs were divided in three groups (n=15): control group (CG), proxymetacaine group (PG) and Ottonia group (OG), which were treated with 0.9% saline, 0.5% proxymetacaine hydrochloride ophthalmic solution and O. martiana extract respectively. An oftalmic evaluation was performed before the treatments. Eye drops were instilled at time 0 (T0) and 3 minutes later (T3). Axial corneal sensitivity was evaluated by esthesiometry 5 and 10 minutes after T0. Tear production and intraocular pressure were evaluated 10 minutes after T0. Slit lamp biomicroscopy was performed 10 and 20 minutes after T0 and the eyes were stained with fluorescein 20 minutes after T0. The STT was reduced in PG. Conjunctival hyperemia was observed in 13 animals from PG and constituted the only ocular alteration observed during the study. Esthesiometry revealed a decreased corneal sensitivity for PG and OG. Those results show that the O. martiana extract acts reducing corneal sensitivity in dogs. Moreover, its use does not decrease the tear production and does not cause any clinical ophthalmic alteration.Keyword: dog, Ottonia martiana, Piperaceae, corneal sensitivity, tear production RESUMO Estudaram-se os efeitos do extrato das folhas de Ottonia martiana sobre a superfície ocular de cães hígidos da raça Beagle. Compuseram-se três grupos de tratamento (n=15): grupo controle (GC), grupo proximetacaína (GP) e grupo Ottonia (GO), tratados, respectivamente, com solução fisiológica, colírio de cloridrato de proximetacaína a 0,5% e extrato de O. martiana. Após avaliação oftálmica inicial, os tratamentos foram realizados no tempo 0 (T0) e decorridos 3min (T3). Avaliaram-se a sensibilidade axial da córnea por estesiometria (T5 e T10) e a produção lacrimal e a pressão ocular (T10). Realizaram-se a biomicroscopia com lâmpada em fenda (T10 e T20), e o teste do tingimento pela fluoresceína (T20

show abstract

Section: Arqsupporting

confidence: 90%

Effects of the Ottonia martiana Miq. (Piperaceae) extract on dog's ocular surface

Lisbão

Correa

Ortiz

et al. 2012

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

show abstract

“…Failure to elicit a reflexive blink in response to corneal stimulation with a 0.5-cm-long filament was designated as maximal corneal anesthesia (complete loss of sensation). 28,29 Corneal sensitivity to stimulation with a 0.5-cm-long filament was defined as notable corneal anesthesia.…”

Section: Methodsmentioning

confidence: 99%

Comparison of peribulbar and retrobulbar regional anesthesia with bupivacaine in cats

Shilo‐Benjamini

Pascoe

Maggs

et al. 2014

ajvr

View full text Add to dashboard Cite

Objective-To compare effectiveness and complications associated with peribulbar and retrobulbar anesthesia with bupivacaine in cats. Animals-6 healthy adult cats. Procedures-Cats were sedated with dexmedetomidine and received a peribulbar injection of 0.5% bupivacaine (1.5 mL), iopamidol (0.5 mL), and saline (0.9% NaCl) solution (1 mL) or retrobulbar injection of 0.5% bupivacaine (0.75 mL) and iopamidol (0.25 mL) in a crossover study with ≥ 2 weeks between treatments. The contralateral eye was the control. Injectate distribution was evaluated with CT. After atipamezole administration, periocular and corneal sensations, intraocular pressure (IOP), and ocular reflexes and appearance were evaluated for 24 hours. Results-All peribulbar and 3 of 6 retrobulbar injections resulted in CT evidence of intraconal injectate. Corneal sensation and periocular skin sensation were absent or significantly reduced relative to that for control eyes for 3 hours after peribulbar injection. Mean ± SD IOP immediately after injection was significantly higher for eyes with peribulbar injections (33 ± 12 mm Hg) than for control eyes or eyes with retrobulbar injections (both 14 ± 4 mm Hg) but 10 minutes later decreased to 18 ± 3 mm Hg. Exophthalmos, chemosis, and ptosis were evident in most injected eyes, and irritation was evident in 3 of 6 peribulbar-injected and 1 of 6 retrobulbar-injected eyes. All conditions resolved within 14 hours. Conclusions and Clinical Relevance-Peribulbar injection resulted in intraconal deposition of bupivicaine in a higher percentage of cats than did retrobulbar injection and induced notable anesthesia relative to that for the control eye; however, IOP increased temporarily.

show abstract

“…Humans over the age of 40 have a significantly reduced corneal sensitivity (Millodot, 1972). Interestingly, the influence of age was not observed in dogs (Barrett et al, 1991) or cats (Blocker and Van Der Woerdt, 2001). These variables were controlled in the present study since a repeated measure statistical design was used with the same testsubjects (paired data), including the initial control.…”

Section: Introductionmentioning

confidence: 99%

“…Discussion It is well known that corneal sensitivity exhibits a great variability and it is influenced by several factors. For instance, corneal sensitivity is significantly reduced in brachycephalic and corneal region evaluated, with the central part being more sensitive that the peripheral cornea in dogs (Barrett et al, 1991) and cats (Blocker and Van Der Woerdt, 2001). Humans over the age of 40 have a significantly reduced corneal sensitivity (Millodot, 1972).…”

Section: Introductionmentioning

confidence: 99%

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs

Cantarella¹,

Oliveira²,

Dorbandt³

et al. 2017

Open Vet J.

View full text Add to dashboard Cite

To evaluate corneal sensitivity by using the Cochet-Bonnet® esthesiometer in normal canine eyes at different time points following instillation of three different topical non-steroidal anti-inflammatory drugs (flurbiprofen sodium 0.03%, diclofenac sodium 0.1% and ketorolac tromethamine 0.5%) and benzalkonium chloride 0.01%. Six healthy mixed breed dogs from the same litter were used in two different stages. First, one drop of flurbiprofen sodium 0.03% and diclofenac sodium 0.1% in each eye; second, one drop of ketorolac tromethamine 0.5% and benzalkonium chloride 0.01% in each eye. Baseline esthesiometry was obtained before eye drop application and every 15 minutes thereafter until a total of 105 minutes of evaluation time. A one-week interval was allowed between the two treatment phases. Statistical analysis was used to compare means according to time of evaluation and drug used. Diclofenac sodium 0.1% decreased corneal sensitivity at 75 and 90 minutes (P > 0.015) with possible interference on neuronal nociceptive activity and analgesic effect while ketorolac tromethamine 0.5% did not show any variation for esthesiometry means along the evaluation. Flurbiprofen sodium 0.03% resulted in increased esthesiometry values 30 minutes after instillation (P > 0.013), increasing corneal sensitivity and possibly producing a greater irritant corneal effect over its analgesic properties. Benzalkonium chloride 0.01% significantly increased corneal sensitivity at 15 minutes of evaluation (P > 0.001), most likely resulting from its irritating effect. Esthesiometry did not allow a definite conclusion over the analgesic effect of the NSAIDs tested; however it was effective in detecting fluctuations in corneal sensitivity.

show abstract

A comparison of corneal sensitivity between brachycephalic and Domestic Short‐haired cats

Abstract: The central cornea is less sensitive in brachycephalic than DSH cats. The central cornea is more sensitive than the peripheral cornea in both brachycephalic and DSH cats.

Cited by 73 publications

References 14 publications

Effects of the Ottonia martiana Miq. (Piperaceae) extract on dog's ocular surface

Effects of the Ottonia martiana Miq. (Piperaceae) extract on dog's ocular surface

Comparison of peribulbar and retrobulbar regional anesthesia with bupivacaine in cats

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs

Contact Info

Product

Resources

About