A comparison of cortisporin and ciprofloxacin otic drops as prophylaxis against post-tympanostomy otorrhea

Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement

“…In addition, some patients are unable to attend daycare/school settings with otorrhea, affecting quality of life. Several prospective studies using ototopical agents have shown a reduction in postoperative otorrhea [5][6][7][8][9][10][11][12][13][14]. In a meta-analysis of five Decrease in incidence of otorrhea with ciprofloxacin/dexamethasone drops prospective studies, ototopical antibiotics or antibiotic/steroid combinations administered perioperatively resulted in a reduction of post-operative otorrhea with the greatest benefit in patients with infection or purulent effusion at the time of surgery [4].…”

“…Many trials have studied the impact of ototopical agents on the rate of otorrhea in the post-operative period [5][6][7][8][9][10][11][12][13][14]. These studies have been conducted in patients at University academic settings.…”

Fungal causes of otitis externa and tympanostomy tube otorrhea

“…Issues of efficacy and toxicity continue to be a matter of debate [4][5][6][7][8][9][10][11][12]. Schrader and Isaacson have postulated that the aggressive use of antibacterial agents within the ear may be a factor in the occurrence of fungal infections of the ear [19].…”

“…There are numerous forms of treatments including topical preparations, systemic therapies and office-based debridement [1,4]. Though several options exist for the treatment otitis externa, the use of ototopical agents in the setting of open middle ear space created by tympanostomy tube insertion or tympanic membrane perforation continues to be debated [4][5][6][7][8][9][10][11][12]. However, the use of ototopicals in the fluoroquinolone class is now more widely accepted.…”

The Relation between Tympanostomy Tube Otorrhea and Types of Immune Cells in Middle Ear Effusion in Children with Otitis Media with Effusion

“…The main problem with ventilation tubes is secondary infection and post-operative otorrhea, which can be managed using antibiotic eardrops. 34,35 However, increasing antibiotic resistance of bacterial pathogens 36 and possible ototoxicity of topical antibiotics 37 can complicate the antimicrobial therapy in post-surgical management of otitis media. Other non-surgical approaches in treatment and prophylaxis of OME include traditional methods, such as combined steroid Á/antimicrobial therapy 38,39 and polyvalent pneumococcal vaccination, 40,41 and relatively new methods based on herbal medicine 42,43 and homeopathy.…”