A Comparison of Culture and GLMM-PCR Methods for Detecting Helicobacter Pylori in Antral and Corpus Biopsy Specimens in Patients with Gastroduodenal Disorders

Nağıyev, Toğrul; Köksal, Fatih; Abaylı, Bahri; Yula, Erkan

doi:10.5336/medsci.2008-9580

Cited by 3 publications

(2 citation statements)

References 2 publications

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“…3,12 Some techniques like immunohistochemistry or molecular techniques like PCR and fluorescent in situ hybridization (FISH) may be helpful for the definitive diagnosis. [15][16] The differential diagnosis includes chronic conjunctivitis and benign lymphoid hyperplasia. 9 In chronic conjunctivitis and benign lymphoid hyperplasia, lymphoid infiltration consists of both CD20--positive B cells and CD3-positive T cells.…”

Section: Discussionmentioning

confidence: 99%

Conjunctival MALT Lymphoma: Case Report

Munğan¹,

Ersöz²,

Türk³

et al. 2012

Turkiye Klinikleri J Med Sci

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A AB BS ST TR RA AC CT T Mucosa associated lymphoid tissue (MALT) lymphoma (marginal zone B-cell lymphoma of MALT according to the World Health Organization classification) is one of the lowgrade non-Hodgkin's lymphomas. The majority of nonHodgkin's lymphomas of the ocular adnexa are extranodal marginal zone B-cell lymphomas of the mucosa associated lymphoid tissue, also known as MALT lymphoma. In 8% of cases, it arises from the conjunctiva. Lymphoid tumors of the conjunctiva may appear as isolated neoplasms or a part of a systemic disease. In this study, we presented a case of primary conjunctival lymphoma and discussed the etiology, diagnosis and treatment with reference to previous studies and reviews. K Ke ey y W Wo or rd ds s: : Lymphoma, B cell, marginal zone; conjunctiva; etiology; therapy Ö ÖZ ZE ET T Mukoza ile ilişkili lenfoid doku (MALT) lenfoması (Dünya Sağlık Örgütü sınıflamasına göre MALT'nin marjinal zon B-hücreli lenfoması) bir düşük dereceli non-Hodgkin lenfoma türüdür. Oküler adneks non-Hodgkin lenfomalarının çoğu MALT lenfoması olarak bilinen, mukozal lenfoid dokunun ekstranodal B-hücreli marjinal zon lenfomasıdır. Hastalık vakaların %8'inde konjonktivadan köken almaktadır. Konjonktivanın lenfoid tümörleri izole bir tümör olarak ya da sistemik bir hastalığın parçası olarak ortaya çıkabilmektedir. Burada, primer konjonktival lenfomalı bir olgu sunulmuş ve önceki çalışmalar ve derlemeler ışığında hastalığın etiyolojisi, tanı ve tedavisi tartışılmıştır. A An na ah ht ta ar r K Ke el li im me el le er r: : Lenfoma, B hücreli, marjinal bölge; konjonktiva; etiyoloji; tedavi

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Section: Discussionmentioning

confidence: 99%

Conjunctival MALT Lymphoma: Case Report

Munğan¹,

Ersöz²,

Türk³

et al. 2012

Turkiye Klinikleri J Med Sci

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“…Helicobacter pylori chronically infects more than half of the world's population and, one of the most frequent causes of gastrointestinal infections and it is estimated that the pathogen has co-evolved with its human host for at least 30.000 years (1)(2)(3)(4)(5). H. pylori infection fulfills each of Koch's postulates as an infectious agent inflicting chronic active gastritis and ulcer.…”

Section: Introductionmentioning

confidence: 99%

Autoimmune extraintestinal manifestations of Helicobacter pylori infection: A bundle of conflicts

Yula¹,

Köksal²

2016

J Immunol Clin Microbiol

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It has been well-known that several microorganisms that have an effect on particular areas of the body might additionally have systemic sequelae. In the last ten years, various studies have been performed on the relationship between Helicobacter pylori infection and a variety of extra digestive illnesses including immunological, hematological, neurological disorders and different pathologies. It has been recommended that complicated interactions between bacterial and host genetic factors, as well as environmental factors, play considerable roles in determining different clinical outcomes. Although, there are conflicting and controversy data in some diseases, in the light of literature, it is currently accepted; that the presence or absence of H. pylori infection might influence the chance of developing of many autoimmune diseases. Treatment of H. pylori infection has been reported to be effective in some diseases like Schoenlein-Henoch purpura, ITP, psoriasis and chronic autoimmune urticaria. This review focuses the possible role of H. pylori infections in various autoimmune diseases taking into account the recent literature.

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Detection of primary clarithromycin resistance of Helicobacter pylori and association between cagA + status and clinical outcome

et al. 2012

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Helicobacter pylori was examined in 110 patients (82 (74.5) with gastritis, 18 (16.4) with duodenitis, six (5.5) with duodenal ulcer and gastroesophageal reflux, and four (3.6 %) with normal) with gastrointestinal problems living in rural area, no history of macrolide use, and detected by culture (71.8) or direct detection from gastric biopsies by PCR (82.7 %). Also, cagA gene was identified using PCR and was found positive in 68/91 (74.7 %) strains. The prevalence of clarithromycin-resistant H. pylori was investigated by two methods including PCR-RFLP (7.7 (A2142G 1.1 and A2143G 6.6 %)) and twofold agar dilution (8.9 %) to detect phenotypic and genotypic status simultaneously. Among all the H. pylori positive patients, eight (8.8 %) isolates were found to be resistant to clarithromycin by at least one of the AD and/or PCR-RFLP methods. H. pylori positive rates were significantly correlated with patients' sex, age, and endoscopic findings (p = 0.040, <0.001 and <0.001, respectively). There were no differences in gender or endoscopic findings related to cagA (+) and cagA (-) patients. The gene of cagA was not significantly helpful in predicting the clinical outcome of H. pylori infection alone. In conclusion, we revealed that there was a low prevalence of primer clarithromycin resistance in patients living in rural area with no history of macrolide use. The prevalence of mutant strains among the macrolide-resistant H. pylori varies even geographically between close provinces.

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A Comparison of Culture and GLMM-PCR Methods for Detecting Helicobacter Pylori in Antral and Corpus Biopsy Specimens in Patients with Gastroduodenal Disorders

Cited by 3 publications

References 2 publications

Conjunctival MALT Lymphoma: Case Report

Conjunctival MALT Lymphoma: Case Report

Autoimmune extraintestinal manifestations of Helicobacter pylori infection: A bundle of conflicts

Detection of primary clarithromycin resistance of Helicobacter pylori and association between cagA + status and clinical outcome

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