2019
DOI: 10.1200/jco.2019.37.4_suppl.81
|View full text |Cite
|
Sign up to set email alerts
|

A comparison of elderly versus nonelderly patients in the CRITICS gastric cancer trial.

Abstract: 81 Background: Although the proportion of elderly cancer patients (pts) increases, few randomized trials provide separate results on this group. Here, we present a sub-analysis of the CRITICS trial, comparing elderly with non-elderly pts. Methods: Preoperative (preop) chemotherapy (CT) included three cycles of epirubicin, cisplatin/oxaliplatin and capecitabine (ECC/EOC); pts were upfront randomized between postoperative (postop) CT (3x ECC/EOC) and chemoradiotherapy (CRT; 45Gy + cisplatin/capecitabine). Elder… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3

Citation Types

0
3
0

Year Published

2019
2019
2019
2019

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(3 citation statements)
references
References 0 publications
0
3
0
Order By: Relevance
“…Slagter et al presented "A comparison of elderly versus nonelderly patients in the CRITICS gastric cancer trial," a large landmark clinical trial with 172 patients, who were 70 years or older. 13 Age correlated with decreased relative dose intensity in preoperative chemotherapy, but this did not affect surgical resection rates and complications. 13 Although older adults were less likely to receive post-operative treatment, older adults were more likely to receive lower doses in the post-operative chemotherapy arm.…”
Section: Reduced Dose Intensity Does Not Affect Survivalmentioning
confidence: 93%
See 2 more Smart Citations
“…Slagter et al presented "A comparison of elderly versus nonelderly patients in the CRITICS gastric cancer trial," a large landmark clinical trial with 172 patients, who were 70 years or older. 13 Age correlated with decreased relative dose intensity in preoperative chemotherapy, but this did not affect surgical resection rates and complications. 13 Although older adults were less likely to receive post-operative treatment, older adults were more likely to receive lower doses in the post-operative chemotherapy arm.…”
Section: Reduced Dose Intensity Does Not Affect Survivalmentioning
confidence: 93%
“…13 Age correlated with decreased relative dose intensity in preoperative chemotherapy, but this did not affect surgical resection rates and complications. 13 Although older adults were less likely to receive post-operative treatment, older adults were more likely to receive lower doses in the post-operative chemotherapy arm. 13 Survival was not significantly different in older versus younger patients.…”
Section: Reduced Dose Intensity Does Not Affect Survivalmentioning
confidence: 93%
See 1 more Smart Citation