A comparison of fatigue correlates in rheumatoid arthritis and osteoarthritis: disparity in associations with disability, anxiety and sleep disturbance

Stebbings, Simon; Herbison, Peter; Doyle, Terrence C. H.; Treharne, Gareth J.; Highton, John

doi:10.1093/rheumatology/kep367

Cited by 107 publications

(94 citation statements)

References 34 publications

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“…As well, 21 percent of the knee osteoarthritis cases and 22.8% of hand osteoarthritis cases had scores greater than 19, rates of clinically depression that were higher than those recorded in a previous study by Abdel-Nasser et al of 10% for adults with knee osteoarthritis, but comparable to cases with rheumatoid arthritis, thought to be a more severe disease, where 23% of the sample were found to have clinically confirmed depression [68]. Similarly, in a study by Stebbings et al [69], participants with osteoarthritis reported greater pain, disability, depression and sleeplessness than those with rheumatoid arthritis (all p<0.01). In those with osteoarthritis, the correlates of fatigue, often not associated strongly with osteoarthritis, were older age (p=0.02), sleep disturbances (p=0.03), depression (p=0.04), disability (p=0.04) and lower C-Reactive Protein (p=0.001).…”

Section: Need For Interventions To Decrease Depressionmentioning

confidence: 80%

Depression and Osteoarthritis: Impact on Disability

Marks¹

2014

Aging Sci

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Osteoarthritis, a highly prevalent progressively disabling chronic health condition associated with aging, is frequently addressed from a physical standpoint, rather than a more holistic standpoint, even though psychological correlates are often prevalent co morbid determinants of this condition. This review briefly summarizes the literature on osteoarthritis and depression published over the last 30 years. From this review, it is concluded that depression is a frequent correlate of osteoarthritis disability, and where present heightens the prevailing disabling painful experience consistently and significantly. Since depression is amenable to treatment, it is recommended more attention to routinely screening for depression among osteoarthritis sufferers, rather than doing this sporadically, is strongly indicated for promoting optimal outcomes among this burgeoning population.

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Section: Need For Interventions To Decrease Depressionmentioning

confidence: 80%

Depression and Osteoarthritis: Impact on Disability

Marks¹

2014

Aging Sci

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“…First, we did not perform a radiographic evaluation of the joints. In RA patients, fatigue had no significant association with pain, disease activity, and disability or bone erosions but was associated with depression and anxiety (25). Therefore, it is unlikely that depression is directly linked to a radiographic evaluation.…”

Section: Discussionmentioning

confidence: 92%

A study on characteristics of rheumatoid arthritis patients achieving remission in depression with 6 months of bDMARDs treatment

et al. 2018

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Objective: To investigate the relationship between baseline factors and depression remission after a 6-month biological disease-modifying antirheumatic drugs (bDMARDs) treatment in rheumatoid arthritis (RA) patients. Methods: The study was conducted in 152 RA patients treated with bDMARDs. The following patient's characteristics were studied: gender, age, disease duration, baseline prednisolone dosage, and serum matrix metalloproteinase3 (MMP3) levels. For assessment, we used the simple disease activity index (SDAI) for RA disease activity, Health Assessment Questionnaire Disability Index (HAQ-DI) for activities of daily living (ADL), Short Form-36 for nonspecific health-related quality of life (QOL), and Hamilton Depression Rating Scale (HAM-D) scores for the depression status. Depressed remission was clarified using HAM-D ≤7 after 6 months of treatment. The patients were divided into two groups according to the presence or absence of depression, and a retrospective study was conducted. Results: Based on binominal logistic analyses, RA patients' with depression remission (n=124) compared to those without depression remission (n=28) had a younger age (p=0.0045, odd ratio: 0.94, 95% confidence interval [CI]:0.8-0.98), female sex (p=0.021, odd ratio:0.21, 95% CI:0.054-0.79), and lower HAM-D scores (p=0.0073, odd ratio:0.85, 95% CI:0.76-0.96) Conclusion: It was proposed that RA patients who are females, younger in age, and have lower depressed scores at baseline can achieve a depression remission status with the bDMARDs treatment.

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“…This VAS had no calibration marks and end descriptors 'Full nights sleep' and 'No sleep at all' . A similar method has been used previously in studies examining the patients with Rheumatoid Arthritis and Osteoarthritis [18].…”

Section: Methodsmentioning

confidence: 99%