A Comparison of Flat and Shallow Conical Tips for Cervical Cryotherapy

Stienstra, K A; Brewer, Benjamin E.; Franklin, LeRoy A.

doi:10.3122/jabfm.12.5.360

Cited by 7 publications

(1 citation statement)

References 16 publications

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“…It consists of a handle device with a metal probe on its tip and a flexible connector that transmits carbon dioxide or nitrous oxide to the probe to freeze and ruin the transformation zone. Although cryotherapy for management of CIN has been advocated by many researchers, 3,10,11 its administration for the relief of recurrent or chronic symptoms of benign CE is under debate. 12-14…”

Section: Introductionmentioning

confidence: 99%

Cryotherapy as a Method for Relieving Symptoms of Cervical Ectopy: A Randomized Clinical Trial

Agah¹,

Sharifzadeh²,

Hosseinzadeh³

2019

Omna Med J

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Objectives Benign cervical ectopy (CE) may cause chronic or recurrent symptoms leading to women repeatedly being referred to gynecology clinics. We aimed to present a safe and effective method for relieving symptoms of CE. Methods This double-blind clinical trial was conducted among 164 women with CE who complained of persistent or recurrent symptoms of cervicitis in the last six months. Patient’s demographic data, medical history, symptoms, and vaginal examination results were recorded. Normal co-test or Pap smear was required to enter the study. Participants were divided into two groups; the intervention group received cryotherapy and the control group underwent cryo-placebo (inserted the probe without true cryotherapy). The outcomes including improvement of symptoms and CE were monitored one, three, and six months later. Results The prevalence of symptoms in the two groups were not significantly different ( p > 0.050). Symptom improvement was significantly higher with cryotherapy: vaginal discharge ( p = 0.006), itching ( p < 0.001), dyspareunia ( p = 0.005), post-coital bleeding ( p = 0.023), and pelvic pain ( p = 0.009). If the symptoms did not disappear, their severity was lower after cryotherapy, comparatively ( p < 0.050). Examination showed more improvement of CE following cryotherapy ( p < 0.001). Cryotherapy showed no remarkable side effects and was associated with more satisfaction ( p < 0.001). Conclusions Cryotherapy is a safe, effective, fast-acting, and cost-benefit therapy that can be considered for the treatment of symptomatic CE.

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