A comparison of frailty indexes for prediction of adverse health outcomes in an elderly cohort

Forti, Paola; Rietti, Elisa; Pisacane, Nicoletta; Olivelli, Valentina; Maltoni, Benedetta; Ravaglia, Giovanni

doi:10.1016/j.archger.2011.01.007

Cited by 62 publications

(84 citation statements)

References 24 publications

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“…The 19 studies analyzed were published between 2001 and 2015 -four in 2013 (20)(21)(22)(23) ; four in 2012 (24)(25)(26)(27) ; three in 2014 (28)(29)(30) ; two in 2011 (31)(32) and in 2007 (33)(34) ; and one in 2015 (35) , 2009 (36) , 2008 (37) and 2001 (7) . As far as the language is concerned, 18 studies were in English (7,(20)(21)(22)(23)(24)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37) and one in Spanish (25) . According to the country of publication, nine studies were carried out in North America (7,20,(24)(25)31,(33)(34)(36)(37) ; In Europe, seven (21)(22)...…”

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

“…As for the publication period, 14 different journals were identified, most notably the Archives of Gerontology and Geriatrics, with three publications (26)(27)32) , and Archives of Internal Medicine (31,37) , BMC Geriatrics (23,28) and Journal of Gerontology (7,33) , with two studies each, and the others, one article (20)(21)(22)(24)(25)(29)(30)(34)(35)(36)(37) . In relation to the method used, 19 studies were longitudinal -14 prospective studies (7,(20)(21)(22)(23)(25)(26)(27)(28)(31)(32)(33)(36)(37) and four retrospective (24,30,(34)(35) -and one randomized case-control study (29) . From the studies that composes the review, 15 (78.9%) had the lowest mean age of the general elderly sample -68.33 (SD=6.73) (25) -and the highest, 84.88 (SD=7.3) (21) years old.…”

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

“…As far as the language is concerned, 18 studies were in English (7,(20)(21)(22)(23)(24)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37) and one in Spanish (25) . According to the country of publication, nine studies were carried out in North America (7,20,(24)(25)31,(33)(34)(36)(37) ; In Europe, seven (21)(22)(23)(26)(27)(28)32) and in Asia and Australia, three (29)(30)35) . As for the publication period, 14 different journals were identified, most notably the Archives of Gerontology and Geriatrics, with three publications (26)(27)32) , and Archives of Internal Medicine (31,37) , BMC Geriatrics (23,28) and Journal of Gerontology (7,33) , with two studies each, and the others, one article …”

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

“…According to the country of publication, nine studies were carried out in North America (7,20,(24)(25)31,(33)(34)(36)(37) ; In Europe, seven (21)(22)(23)(26)(27)(28)32) and in Asia and Australia, three (29)(30)35) . As for the publication period, 14 different journals were identified, most notably the Archives of Gerontology and Geriatrics, with three publications (26)(27)32) , and Archives of Internal Medicine (31,37) , BMC Geriatrics (23,28) and Journal of Gerontology (7,33) , with two studies each, and the others, one article (20)(21)(22)(24)(25)(29)(30)(34)(35)(36)(37) . In relation to the method used, 19 studies were longitudinal -14 prospective studies (7,(20)(21)(22)(23)(25)(26)(27)…”

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

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Fall and its association with the frailty syndrome in the elderly: systematic review with meta-analysis

Fhon

Rodrigues

Neira

et al. 2016

Rev. esc. enferm. USP

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Objective:To analyze the prevalence of falls and frailty syndrome and the association between these two syndromes in the elderly population. Method: Systematic review, without restriction of dates, in English, Portuguese and Spanish languages, in the databases PubMed, CINAHL, LILACS and in the SciElo virtual library. The association between both variables was extracted from the studies (Odds Ratio and 95% Confidence Intervals). Results: The review included 19 studies published between 2001 and 2015. The prevalence of falls in the frail elderly population was between 6.7% and 44%; in the pre-frail, between 10.0% and 52.0%, and in the non-frail, between 7.6% and 90.4%. The association between both variables presented a value of OR 1.80 (95% CI 1.51-2.13). Conclusion: There is evidence that falls are associated to the frailty in the elderly. Other factors may influence this association, such as age, sex, data collection instrument of the studies, place where they live and the process of senescence. DESCRIPTORSAged; Accidental Falls; Frail Elderly; Geriatric Nursing; Review.Fall and its association with the frailty syndrome in the elderly: systematic review with meta-analysis Queda e sua associação à síndrome da fragilidade no idoso: revisão sistemática com metanálise Caída y su asociación con el síndrome de la fragilidad en el adulto mayor: revisión sistemática con metaanálisis

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Section: Identification and Selection Of Studiesmentioning

confidence: 99%

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

Section: Identification and Selection Of Studiesmentioning

confidence: 99%

See 2 more Smart Citations

Fall and its association with the frailty syndrome in the elderly: systematic review with meta-analysis

Fhon

Rodrigues

Neira

et al. 2016

Rev. esc. enferm. USP

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“…Polypathological scale) [4,5,10,11,20,21,[77][78][79]. Most studies indicate a level of frailty for community-dwelling older adults between 5 and 15%.…”

Section: How Prevalent Is Frailty?mentioning

confidence: 99%

Musculoskeletal health, frailty and functional decline

Milte

Crotty

2014

Best Practice & Research Clinical Rheumatology

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Frailty in older people is associated with a vulnerability to adverse events. While ageing is associated with a loss of physiological reserves identifying those with the syndrome of frailty has the potential to assist clinicians tailor treatments to those at risk of future decline into disability with increased risk of complications, morbidity and mortality. Sarcopenia is a key component of the frailty syndrome and on its own puts older people at risk of fragility fractures however the clinical syndrome of frailty affects musculoskeletal and non musculoskeletal systems. Hip fractures are becoming a prototype condition in the study of frailty. Following a hip fracture many of the interventions are focused on limiting mobility disability and restoring independence with activities of daily living but there are multiple factors to be addressed including osteoporosis, sarcopenia, delirium, weight loss. Established techniques of geriatric evaluation and management allow systematic assessment and intervention on multiple components by multidisciplinary teams and deliver the best outcomes. Using the concept of frailty to identify older people with musculoskeletal problems as at risk of a poor outcome assists in treatment planning and is likely to become more important as effective pharmacological treatments for sarcopenia emerge. This review will focus on the concept of frailty and its relationship with functional decline, as well as describing its causes, prevalence, risk factors and potential clinical applications and treatment strategies. Key wordsFragility fracture, frailty, functional decline, screening, older adult, exercise therapy, dietary therapy Word count 9,401 words (word limit=9,400)

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Frailty in childhood cancer survivors

Ness

Armstrong

Kundu

et al. 2014

Cancer

148

102

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Young adult childhood cancer survivors are at increased risk for frailty, a physiologic phenotype typically found among older adults. This phenotype is associated with new onset chronic health conditions and mortality among both older adults and among childhood cancer survivors. Mounting evidence suggests that poor fitness, muscular weakness and cognitive decline are common among adults treated for childhood malignancies, and that risk factors for these outcomes are not limited to those treated with cranial radiation. Although the pathobiology of this phenotype is not known, early cellular senescence, sterile inflammation and mitochondrial dysfunction in response to initial cancer or treatment related insults are hypothesized to play a role. Interventions to prevent or remediate frailty among childhood cancer survivors have not been tested. Pharmaceutical, nutriceutical and lifestyle interventions show some promise.

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A comparison of frailty indexes for prediction of adverse health outcomes in an elderly cohort

Cited by 62 publications

References 24 publications

Fall and its association with the frailty syndrome in the elderly: systematic review with meta-analysis

Fall and its association with the frailty syndrome in the elderly: systematic review with meta-analysis

Musculoskeletal health, frailty and functional decline

Frailty in childhood cancer survivors

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