A comparison of liquid‐based cytology with conventional cytology

Abstract

The liquid-based and conventional cytology methods were found to be equivalent in the detection of cervical epithelial abnormalities.

A Comparison of Liquid-Based Cytology with Conventional Cytology in Cervical Cancer Screening

“…This study showed that the LBC method resulted in a significantly lower percentage of unsatisfactory specimens than the conventional method. Many prior reports have suggested that the LBC method produces a lower percentage of unsatisfactory specimens [1,2,3,4,5,6,7,8,9,10]. In studies reporting no difference in the reduction of unsatisfactory specimens, the rates were lower than those in a meta-analysis [16] and other reports (LBC method 0.3% vs. conventional method 1.1%) [17].…”

“…In addition, the Bethesda system (TBS; 2001), which outlines cytological diagnostic criteria for cervical smears, is only gradually being adopted. It has been reported that the liquid-based cytology (LBC) method is useful for reducing the number of unsatisfactory specimens [1,2,3,4,5,6,7,8,9,10]. Unsatisfactory specimens are ≤1.1%, and one of the most common reasons for unsatisfactory specimens was too few squamous cells [11].…”

“…Unsatisfactory specimens are ≤1.1%, and one of the most common reasons for unsatisfactory specimens was too few squamous cells [11]. In addition, some reports have stated that the LBC method is associated with a higher cancer detection rate than the conventional method [1,8,12,13,14,15], whereas other reports found no difference between both methods [2,3,4,7,9,16,17,18,19,20]. According to meta-analyses and randomized studies, the number of unsatisfactory slides was not lower, or detection of high-grade lesions was not increased compared with conventional cytology [16,17].…”

Zeynep Kamil Kadın Doğum Ve Çocuk Hastanesindeki 50,645 servikal smear sonucunun değerlendirilmesi.

“…Eroğlu ve arkadaşlarının çalışmasında %0.5, %0, %0.02, %0.02 (18), Öner ve arkadaşlarının çalışmasın-da ise %1.08, %0, %0.036, %0.036 dir (19). Çelik ve arkadaşlarının çalışması ise en yük-sek değerlere sahiptir; toplam atipik skuamöz hücrelerin (ASC) oranı %4.8, LSIL %1.8, HSIL %1.1, AGUS %0.9 dur (20). Türkiye genelini yansıtan aynı grubun (TSK ve SSA grup) ça-lışmasında bu oranlar sırasıyla %1.07, %0.07, %0.3, %0.17 ve %0.08 dir (14).…”

Comparison of Cervical Cell Morphology Using Two Different Cytology Techniques for Early Detection of Pre-Cancerous Lesions

“…According to one study LBC enhance the specimen adequacy, decrease the count of unsatisfactory smears and improves screening results (Celik et al, 2008). Liquid based cytology also improves adequacy by increase in cellularity (Nandini et al, 2012).…”