1996
DOI: 10.1056/nejm199603143341101
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A Comparison of Low-Molecular-Weight Heparin Administered Primarily at Home with Unfractionated Heparin Administered in the Hospital for Proximal Deep-Vein Thrombosis

Abstract: Low-molecular-weight heparin can be used safely and effectively to treat patients with proximal deep-vein thrombosis at home.

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Cited by 1,141 publications
(665 citation statements)
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“…In this cohort of postarthroplasty patients, the incidence of major bleeding complications (10%) was substantially higher than the rates reported for nonsurgical patients, which are 0% to 5% [5,20,22,35]. This difference highlights the unique risks inherent to anticoagulation treatment in patients who have undergone procedures, which include substantial soft tissue dissection and osteotomies.…”
Section: Discussionmentioning
confidence: 63%
“…In this cohort of postarthroplasty patients, the incidence of major bleeding complications (10%) was substantially higher than the rates reported for nonsurgical patients, which are 0% to 5% [5,20,22,35]. This difference highlights the unique risks inherent to anticoagulation treatment in patients who have undergone procedures, which include substantial soft tissue dissection and osteotomies.…”
Section: Discussionmentioning
confidence: 63%
“…Moreover, two major RCTs have also established that the outpatient administration of LMWH is as safe as unfractionated heparin administered in hospital for the treatment of DVT [42][43][44]. For these reasons, outpatient treatment of patients with DVT, with or without asymptomatic PE, has become common practice worldwide.…”
Section: Discussionmentioning
confidence: 99%
“…Patients with acute deep vein thrombus (DVT) can safely be treated as outpatients [1][2][3][4]. Outpatient treatment of DVT is recommended with grade 1B evidence in the most recent American College of Chest Physicians (ACCP) guidelines [5].…”
Section: Introductionmentioning
confidence: 99%