A comparison of patient-reported outcomes between Alloderm and Dermacell in immediate alloplastic breast reconstruction: A randomized control trial

Stein, Michael J.; Arnaout, Angel; Lichtenstein, Julia B.; Frank, Simon G.; Cordeiro, Erin; Roberts, Amanda; Ghaedi, Bahareh; Zhang, Jing

doi:10.1016/j.bjps.2020.08.018

Cited by 10 publications

(13 citation statements)

References 22 publications

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“…All types of BRS yielded improvements with breast satisfaction following surgery and continued to improve over time except for Stein et al and Negenborn et al, who notably used ADM alongside tissue expanders/implant BRS. 41 , 50 In these surgeries, lower satisfaction with breast/s, overall outcome, physical and sexual wellbeing outcomes following BRS were observed. 41 , 50 A possible explanation for these findings is that ADM is associated with higher post-operative complications including seroma, infections, and red breast syndrome which may affect patient QoL and satisfaction.…”

Section: Discussionmentioning

confidence: 94%

“… 41 , 50 In these surgeries, lower satisfaction with breast/s, overall outcome, physical and sexual wellbeing outcomes following BRS were observed. 41 , 50 A possible explanation for these findings is that ADM is associated with higher post-operative complications including seroma, infections, and red breast syndrome which may affect patient QoL and satisfaction. 41 , 50 , 56 , 57 Another factor that worsened BREAST-Q scores was radiotherapy, which is also associated with higher rates of complications in autologous and implant-based BRS.…”

Section: Discussionmentioning

confidence: 94%

“…Most studies compared PROs between different types of BRS. Comparisons were based on timing (immediate versus delayed), 25–27 type (implant-based versus autologous), 28–37 type of flap used (deep inferior epigastric perforators [DIEP], transverse rectus abdominis myocutaneous [TRAM], latissimus dorsi [LD] flaps), 38–40 type of Implant/tissue expanders used (acellular dermal matrices [ADM], silicone expanders, saline expanders), 41–44 placement of implant (pre-pectoral versus sub-pectoral), 45 , 46 number of stages (single stage versus multiple stages), 25–27 , 45 weight (normal weight, overweight, obese), 47 and age (less than 60 versus over 60, less than 65 versus over 65). 39 , 48 …”

Section: Resultsmentioning

confidence: 99%

“… 41 , 50 A possible explanation for these findings is that ADM is associated with higher post-operative complications including seroma, infections, and red breast syndrome which may affect patient QoL and satisfaction. 41 , 50 , 56 , 57 Another factor that worsened BREAST-Q scores was radiotherapy, which is also associated with higher rates of complications in autologous and implant-based BRS. 33 , 58 , 59 Knowing the difference in complication rates in these BRS cohorts would better explain the low level of satisfaction observed.…”

Section: Discussionmentioning

confidence: 99%

“… 60 Another domain, sexual wellbeing, generally decreased following mastectomy compared with pre-operative BREAST-Q scores, and after BRS there was reportedly worsened to minimal improvements. 41 , 42 , 61 Overall, sexual wellbeing fared the least compared to all other domains which can be explained by the psychological effects of breast cancer surgery which can include anxiety, depression, and a feeling of loss of femininity. 62 Moreover, pain and discomfort in the months following surgery may impact the pursuit or desire for sexual activity.…”

Section: Discussionmentioning

confidence: 99%

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Systematic Review of Breast-Q: A Tool to Evaluate Post-Mastectomy Breast Reconstruction

Seth¹,

Seth²,

Bulloch³

et al. 2021

BCTT

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Purpose The aim of this systematic review is to update and synthesize new evidence on BREAST-Q questionnaire’s ability to reflect patient-reported outcomes in women who have undergone breast reconstruction surgery (BRS) following mastectomy. Methods PubMed, Science Direct, Google Scholar, Cochrane CENTRAL, and Clincaltrial.gov were searched for relevant studies from January 2009 to September 2021. Any interventional or observational studies that used BREAST-Q to assess patient-reported outcomes in the assessment of BRS following mastectomy were included. Results A total of 42 studies were eligible for inclusion in the review. Three were randomized controlled trials and 39 were observational studies. Compared with pre-operative scores, there was an improvement in all BREAST-Q outcome domains following BRS including ‘satisfaction with breasts’, “satisfaction with outcome” “psychosocial”, “physical”, and “sexual wellbeing”. Sexual well-being had the lowest BREAST-Q score both pre-and post-operatively (37.8–80.0 and 39.0–78.0, respectively). Autologous BRS reports higher satisfaction and overall wellbeing compared to implant-based BRS. BREAST-Q has a higher and narrow internal consistency of 0.81 to 0.96 compared with other patient-reported outcome measures (PROMs; EORTC-QLQ, FACT-B, BR-23, BCTOS). The BREAST-Q questionnaire is the only PROM which allows patients to reflect on their care, surgical outcomes, and satisfaction collectively. Conclusion This review highlights the fact that BREAST-Q can effectively and reliably measure satisfaction and wellbeing of breast cancer patients after BRS. Comparatively, sexual wellbeing shows poorer outcomes following BRS and more longitudinal studies are necessary to understand the basis for these findings. Compared to other PROMs, BREAST-Q is reliable and specific to breast cancer surgery. Overall, BREAST-Q can help clinicians improve their quality of service, understand patient experiences, and may be used as an auditing tool for surgical outcomes.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Systematic Review of Breast-Q: A Tool to Evaluate Post-Mastectomy Breast Reconstruction

Seth¹,

Seth²,

Bulloch³

et al. 2021

BCTT

View full text Add to dashboard Cite

show abstract

Trends and issues in clinical research on satisfaction and quality of life after mastectomy and breast reconstruction: a 5-year scoping review

et al. 2023

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Breast reconstruction (BR) aims to improve the satisfaction and quality of life (QOL) of breast cancer survivors. Clinical studies using patient-reported outcomes (PROs) can therefore provide relevant information to the patients and support decision-making. This scoping review was conducted to analyze recent trends in world regions, methods used, and factors investigated. The literature search was conducted in August 2022. Databases of PubMed, MEDLINE, and CINAHL were searched for relevant English-language studies published from 2017 to 2022. Studies involving women with breast cancer who underwent BR after mastectomy and investigated PROs after BR using BR-specific scales were included. Data on the country, publication year, study design, PRO measures (PROMs) used, time points of surveys, and research themes were collected. In total, 147 articles met the inclusion criteria. BREAST-Q was the most widely used, contributing to the increase in the number and diversification of studies in this area. Such research has been conducted mainly in North America and Europe and is still developing in Asia and other regions. The research themes involved a wide range of clinical and patient factors in addition to surgery, which could be influenced by research methods, time since surgery, and even cultural differences. Recent BR-specific PROMs have led to a worldwide development of research on factors that affect satisfaction and QOL after BR. PRO after BR may be influenced by local cultural and social features, and it would be necessary to accumulate data in each region to draw clinically useful conclusion.

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Reporting of patient-reported outcomes amongst randomized clinical trials in plastic surgery: a systematic review using CONSORT-PRO

Milazzo,

Yuan,

Graham

et al. 2024

Journal of Plastic, Reconstructive & Aesthetic Surgery

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A comparison of patient-reported outcomes between Alloderm and Dermacell in immediate alloplastic breast reconstruction: A randomized control trial

Cited by 10 publications

References 22 publications

Systematic Review of Breast-Q: A Tool to Evaluate Post-Mastectomy Breast Reconstruction

Systematic Review of Breast-Q: A Tool to Evaluate Post-Mastectomy Breast Reconstruction

Trends and issues in clinical research on satisfaction and quality of life after mastectomy and breast reconstruction: a 5-year scoping review

Reporting of patient-reported outcomes amongst randomized clinical trials in plastic surgery: a systematic review using CONSORT-PRO

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