A COMPARISON OF PGE<sub>2</sub> AND PGF<sub>2α</sub> VAGINAL GEL FOR RIPENING THE CERVIX BEFORE INDUCTION OF LABOUR

Mackenzie, I. Z.; Embrey, M. P.

doi:10.1111/j.1471-0528.1979.tb10588.x

Cited by 66 publications

(12 citation statements)

References 9 publications

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“…Similar finding was made by Mackenzie IZ et al [7] Nunes F et al could detect any significant difference in the incidence of maternal and perinatal complications between Misoprostone and Dinoprostone groups. The present study finding reaffirmed this.…”

Section: Discussionsupporting

confidence: 78%

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Induction of Labour by Intravaginal Misosprostol and Intracervical Dinoprostone: A Comparative Study

Th¹,

Sanaton²

2018

AIMDR

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Background: Induction of labour is indicated when the benefits to either the mother or foetus outweigh those of continuing the pregnancy. Many drugs or methods have been tried for the purpose, the latest addition being prostaglandins. Objective: The present study was taken up to compare the safety and efficacy of 50 µg intra-vaginal Misoprostol and a single dose of 0.5 mg intra-cervical Dinoprostone in induction of labour. Methods: 220 women admitted in RIMS during the period Jan 2003-Aug 2004 and needing induction of labour were randomly allocated into two groups, each group consisting of 110 women. To one group Misoprostol was given while the other group got Dinoprostone. These two groups were followed up up-to the perinatal period. Result: The mean Bishop's score at 4th hour were found to be significantly increased in both the groups, the mean score at 4th hour being significantly higher in Misoprostol group as compared to Dinoprostone group (5.77 Vs 4.83). The need for oxytocin augmentation was significantly less in Misoprostol group. The induction-delivery period was also found to be much shorter in this group when compared to Dinoprostone group (10.8±4.8 hours Vs 12.0±7.7 hours). The proportion of vaginal delivery was comparable in the two groups. Apgar scores of babies in the two groups also were comparable. Maternal and perinatal complications were very less in both the groups. Conclusion: Both intra-vaginal Misoprostol and intra-cervical Dinoprostone were found to be effective and safe for induction of labour. However, Misoprotol is less expensive, easy to administer and more effective than Dinoprostone with minimal side effects when cases are monitored properly.

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Section: Discussionsupporting

confidence: 78%

“…[7][8][9] In the present study, the main indication was PROM (38.6%) followed by PDP (28.6%). The reason may be that after reaching term, the efficiency of placenta starts to diminish and the foetus suffers increasingly from anoxia.…”

Section: Discussionmentioning

confidence: 99%

Induction of Labour by Intravaginal Misosprostol and Intracervical Dinoprostone: A Comparative Study

Th¹,

Sanaton²

2018

AIMDR

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“…Cases of uterine hypertonus and fetal bradycardia have been reported following the use of prostaglandin (MacKenzie and Embrey, 1978;MacKenzie and Embrey, 1979) and this necessitates cardiotocographic monitoring of the mother and fetus when these potent agents are used. Cases of uterine hypertonus and fetal bradycardia have been reported following the use of prostaglandin (MacKenzie and Embrey, 1978;MacKenzie and Embrey, 1979) and this necessitates cardiotocographic monitoring of the mother and fetus when these potent agents are used.…”

Section: Discussionmentioning

confidence: 99%

The Use of Foley's Catheter in Ripening the Unfavourable Cervix Prior to Induction of Labour

Ezimokhai

Nwabineli

1980

BJOG

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Foley's catheter was used to ripen the cervix prior to induction of labour in 21 primigravidae and the results compared with those obtained using 5 mg of prostaglandin E, in vaginal gel in another group of 14 primigravidae. The improvement in cervical score and outcome of induction of labour was similar in both groups. There were no complications attributable to the use of these agents. Foley's catheter is easy to use, cheap and readily available.

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“…[8][9][10] The expected date of delivery was confirmed by ultrasonographic examination, patients earliest pelvic examination and per abdominal examination.…”

Section: Discussionmentioning

confidence: 99%

Incidence of cesarean delivery after induction of labour with dinoprostone gel at term in nulliparous women with unfavourable bishops score

Mehta¹,

Kumar²,

Fathepuriya³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: The aim of induction of labour is to achieve vaginal delivery in advance of the normal timing of parturition and to avoid operative delivery. The objective was to study the incidence of instrumental delivery and cesarean section in nulliparous women with unfavourable bishops score at term.Methods: This study was conducted on 200 patients in nulliparous women with unfavourable bishop score, cephalic presentation and no previous history of abortion.Results: The most frequent cause of induction of labour was postdatism (47.5%) followed by PIH (25.5%) and PROM (13%). 143 (71.5%) women had normal vaginal delivery whereas in 54 women (27%) cesarean section was done. 2 women (1%) had forceps application for delivery and remaining 1 women (0.5%) had ventouse delivery. Out of 200 patients 9 had maternal complication of induction of labour.Conclusions: In present study 71.5% women had normal vaginal delivery, 27% had cesarean section. Mean bishop score at induction was 3.31 which improved to 4.0 after 12 hours of gel instillation. The mean induction to delivery interval was 13.38 hrs in present study, 54.5% patients were delivered within 12 hours of gel instillation in this study. Most common indication of cesarean section was failed progress followed by fetal distress.

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A COMPARISON OF PGE₂ AND PGF_2α VAGINAL GEL FOR RIPENING THE CERVIX BEFORE INDUCTION OF LABOUR

Cited by 66 publications

References 9 publications

Induction of Labour by Intravaginal Misosprostol and Intracervical Dinoprostone: A Comparative Study

Induction of Labour by Intravaginal Misosprostol and Intracervical Dinoprostone: A Comparative Study

The Use of Foley's Catheter in Ripening the Unfavourable Cervix Prior to Induction of Labour

Incidence of cesarean delivery after induction of labour with dinoprostone gel at term in nulliparous women with unfavourable bishops score

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A COMPARISON OF PGE2 AND PGF2α VAGINAL GEL FOR RIPENING THE CERVIX BEFORE INDUCTION OF LABOUR

Cited by 66 publications

References 9 publications

Induction of Labour by Intravaginal Misosprostol and Intracervical Dinoprostone: A Comparative Study

Induction of Labour by Intravaginal Misosprostol and Intracervical Dinoprostone: A Comparative Study

The Use of Foley's Catheter in Ripening the Unfavourable Cervix Prior to Induction of Labour

Incidence of cesarean delivery after induction of labour with dinoprostone gel at term in nulliparous women with unfavourable bishops score

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A COMPARISON OF PGE₂ AND PGF_2α VAGINAL GEL FOR RIPENING THE CERVIX BEFORE INDUCTION OF LABOUR