A Comparison of Portal Vein Embolization With Poly(2-hydroxyethylmethacrylate) and a Histoacryl/Lipiodol Mixture in Patients Scheduled for Extended Right Hepatectomy

Abstract

ght hepatectomy and whether it is as effective as the currently used agent (a histoacryl/lipiodol mixture). Two groups of nine patients each scheduled for extended right hepatectomy for primary or secondary hepatic tumor, had right portal vein embolization in an effort to induce future liver remnant (FLR) hypertrophy. One group had embolization with PHEMA, the other one with the histoacryl/lipiodol mixture. In all patients, embolization was performed using the right retrograde transhepatic access. Embolization was technically successful in all 18 patients, with no complication related to the embolization agent. Eight patients of either group developed FLR hypertrophy allowing extended right hepatectomy. Likewise, one patient in each group had recanalization of a portal vein branch. Histology showed that both embolization agents reach the periphery of portal vein branches, with PHEMA penetrating somewhat deeper into the periphery. PHEMA has been shown to be an agent suitable for embolization in the portal venous system comparable with existing embolization agent (histoacryl/lipiodol mixture).

True Story of Poly(2-Hydroxyethyl Methacrylate)-Based Contact Lenses: How Did It Really Happen

“…Of the other applications, known are implants for otorhinolaryngology, 49,50 plastic or general surgery, 51 gynecology, 52 urology, 53 and neurology, 54 as well as carriers for cell cultivation for dermal wounds healing, burns, or bedsores. 55,56 Polymers of HEMA are still used to prepare ointments/salves 57 and various gel preparations, 58 drug carriers, 59 tissue expanders, 60 synthetic emboli 61 , or hemoperfusion detoxicating columns. 62 3D microstructured carriers for cell cultivation, known as scaffolds, have since recently been used.…”