A comparison of postoperative cognitive function and pain relief with fentanyl or tramadol patient-controlled analgesia

Ng, Kkc; Yuen, T. S. T.; Ng, Vivian M.W.

doi:10.1016/j.jclinane.2005.08.004

Cited by 35 publications

(19 citation statements)

References 24 publications

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“…Other studies have demonstrated that PCA tramadol is as effective as PCA morphine control following major surgery 17,18 . In clinical trials, observers found that tramadol can also be used as an additional agent with other opioids.…”

Section: Discussionmentioning

confidence: 96%

Comparative study of intravenous opioid consumption in the postoperative period

Saraçoğlu¹,

Saraçoğlu²,

Cakar³

et al. 2012

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Section: Discussionmentioning

confidence: 96%

Comparative study of intravenous opioid consumption in the postoperative period

Saraçoğlu¹,

Saraçoğlu²,

Cakar³

et al. 2012

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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“…One frequently used opioid, meperidine, is among one of the most blamed agents. It has been argued that morphine hydrochloride causes less cognitive dysfunction and delirium than tramadol and meperidine (36,37). In our 24-h postoperative patient follow-up, we administered additional doses of morphine according to the VNS.…”

Section: Discussionmentioning

confidence: 99%

The effect of total intravenous anesthesia on the postoperative cognitive functions of young and elderly patients after lumbar disk surgery

Ilvan¹,

Özköse²

2015

Turk J Med Sci

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Background/aim: The negative effects of surgery and anesthesia on cognitive functions and their relationships with many factors are well known. In the present study we aimed to investigate the effect of the total intravenous anesthesia (TIVA) method on the postoperative cognitive functions between young and elderly patients scheduled to undergo lumbar disk surgery. Materials and methods:The TIVA method was applied to 40 patients less than 65 years old (young, Group Y) and ≥65 years old (old, Group O), whose Mini Mental State Examination (MMSE) results and serum S-100 beta protein levels were compared preoperatively and postoperatively at the 24th hour.Results: Postoperative cognitive dysfunction was not observed in any of the groups in the early stage. MMSE results and mean S-100 beta protein levels determined before and after the operation did not have statistically significant differences between the groups over time. Conclusion:In the present study, the TIVA method did not affect postoperative early cognitive functions in either old or young patients who underwent lumbar disk surgery.

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“…There was no statistically significant difference in the rates of confusion between morphine and fentanyl but the rates were 4.3% for patients given fentanyl and 14.3% for those receiving morphine; there was less depression of cognitive function with fentanyl Level II). Compared with morphine, no differences in cognitive function were reported in patients receiving tramadol (Silvasti et al, 2000 Level II; Ng et al, 2006 Level II), but cognitive function was poorer in patients given hydromorphone (Rapp et al, 1996 Level II). Studies of lower quality reported a significantly greater incidence of delirium with pethidine compared with morphine (Adunsky et al, 2002 Level III-3) and a variety of other opioids CHAPTER 4 Level III-2).…”

Section: Cognitive Function and Confusionmentioning

confidence: 99%

Safety of opioid patch initiation in Australian residential aged care

Gadzhanova

Roughead

Pont

2015

Medical Journal of Australia

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Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design: A cross‐sectional cohort study, analysing pharmacy data on individual patient supply between 1 July 2008 and 30 September 2013. Setting: Sixty residential aged care facilities in New South Wales. Participants: Residents receiving an initial opioid patch during the study period. Main outcome measure: The proportion of residents who were opioid‐naive in the 4 weeks prior to patch initiation was determined. In addition, the patch strength at initiation and the daily dose of transdermal patches and of additional opioids 1 month after initiation were determined. Results: An opioid patch was initiated in 596 of 5297 residents (11.3%: 2.6% fentanyl, 8.7% buprenorphine) in the 60 residential aged care facilities. The mean age at initiation was 87 years, and 74% of the recipients were women. The proportion of recipients who were opioid‐naive before patch initiation was 34% for fentanyl and 49% for buprenorphine. Most were initiated at the lowest available patch strength, and the dose was up‐titrated after initiation. Around 15% of fentanyl users and 10% of buprenorphine users needed additional regular opioids after patch initiation. Conclusions: The results suggest some inappropriate initiation of opioid patches in Australian residential aged care facilities. Contrary to best practice, a third of residents initiated on fentanyl patches were opioid‐naive in the 4 weeks before initiation.

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A comparison of postoperative cognitive function and pain relief with fentanyl or tramadol patient-controlled analgesia

Cited by 35 publications

References 24 publications

Comparative study of intravenous opioid consumption in the postoperative period

Comparative study of intravenous opioid consumption in the postoperative period

The effect of total intravenous anesthesia on the postoperative cognitive functions of young and elderly patients after lumbar disk surgery

Safety of opioid patch initiation in Australian residential aged care

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