2017
DOI: 10.1007/s00066-017-1160-7
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A comparison of swallowing dysfunction after three-dimensional conformal and intensity-modulated radiotherapy

Abstract: Despite several methodological limitations, reports from the current literature seem to suggest better swallowing outcomes with IMRT compared to 3DCRT. Further improvements are likely to result from the increased use of IMRT plans optimized for SWOAR sparing.

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Cited by 35 publications
(21 citation statements)
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“…Advances in head and neck surgery have led from radical neck dissection to selective neck dissection in selected patients with squamous cell carcinoma of the oral cavity, pharynx and larynx [36]. In radiation oncology modern techniques such as IMRT or VMAT combined with image-guidance allow a higher precision in dose application and therefore individualized treatment approaches should be investigated [37][38][39][40]. The aim of the DIREKHT trial is to reduce late toxicity after postoperative radiotherapy without increasing locoregional failure.…”
Section: Discussionmentioning
confidence: 99%
“…Advances in head and neck surgery have led from radical neck dissection to selective neck dissection in selected patients with squamous cell carcinoma of the oral cavity, pharynx and larynx [36]. In radiation oncology modern techniques such as IMRT or VMAT combined with image-guidance allow a higher precision in dose application and therefore individualized treatment approaches should be investigated [37][38][39][40]. The aim of the DIREKHT trial is to reduce late toxicity after postoperative radiotherapy without increasing locoregional failure.…”
Section: Discussionmentioning
confidence: 99%
“…To date, despite the rationale to use IMRT to reduce posttreatment dysphagia has been well acknowledged, this assumption is still to be confirmed due to the heterogeneity of the current clinical data. Nevertheless, a positive trend seems to emerge by the literature data reporting an overall lower pattern of aspiration after IMRT compared with 3DCRT (2.6-7% versus 7-78%, respectively) and is likely to increase as the radiation oncologist will be more and more encouraged to optimize plans to SWOARs in their clinical practice [59].…”
Section: Intensity and Modulated Radiotherapy (Imrt) As A Strategy Tomentioning
confidence: 99%
“…The irradiated dose and volume to these critical organs is a major determinant for RT toxicity as well as for irradiating adequate dose to target volume. Compared to 3D-CRT, the use of IMRT not only increased treatment outcomes but also reduced toxicity significantly [23][24][25]. Many expect further benefit from the use of proton therapy [26].…”
Section: Head and Neck Cancermentioning
confidence: 99%