A Comparison of Tear Volume (by Tear Meniscus Height and Phenol Red Thread Test) and Tear Fluid Osmolality Measures in Non-Lens Wearers and in Contact Lens Wearers

Miller, William L.; Doughty, Michael J.; Narayanan, Srihari; Leach, Norman E.; Tran, Anthony; Gaume, Amber; Bergmanson, Jan P.G.

doi:10.1097/01.icl.0000138714.96401.2b

Cited by 80 publications

(60 citation statements)

References 20 publications

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“…Previous studies measuring tear osmolarity in contact lens wearers demonstrated increased tear osmolarity during wear time [1,3,11,17]. Similar results with both hydrogel and silicone hydrogel daily disposable contact lenses were obtained in our study.…”

Section: Discussionsupporting

confidence: 80%

Comparison of tear osmolarity and ocular comfort between daily disposable contact lenses: hilafilcon B hydrogel versus narafilcon A silicone hydrogel

Saraç¹,

Gürdal²,

Bostancı-Ceran³

et al. 2012

Int Ophthalmol

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The aim of this study was to evaluate tear osmolarity and ocular comfort with two different types of hydrogel daily disposable lenses. The right eyes of 15 first-time contact lens users were included in this prospective study. All eyes wore hilafilcon B silicone hydrogel contact lenses for 8 h (group 1). After 1 week without contact lenses, all eyes wore narafilcon A silicone hydrogel contact lenses for 8 h (group 2). Tear osmolarity measurement was performed before and after 4 and 8 h of each contact lens wear. Ocular comfort was assessed after 4 and 8 h of each contact lens wear. In group 1, the mean baseline, 4- and 8-h tear osmolarity values were 293 ± 10.57, 303.00 ± 10.5 mOsm/L (p = 0.023), and 295.0 ± 1.4 mOsm/L (p > 0.05), respectively. In group 2, the mean baseline, 4- and 8-h tear osmolarity values were 294 ± 13.65, 300.9 ± 11.3 mOsm/L (p = 0.007), and 298.80 ± 7.2 mOsm/L (p > 0.05), respectively. In group 1, the mean comfort score was 7.20 ± 0.45 and 8.60 ± 0.45 at 4 and 8 h, respectively (p = 0.038). In group 2, the mean comfort score significantly decreased from 9.80 ± 0.45 to 7.80 ± 0.84 at 4 h (p = 0.039). Both hydrogel and silicone hydrogel daily disposable contact lenses elevated tear osmolarity during 8 h of contact lens wear. The increase in tear osmolarity with both contact lenses was below the cut-off value for dry eye and was not associated with ocular comfort.

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Section: Discussionsupporting

confidence: 80%

Comparison of tear osmolarity and ocular comfort between daily disposable contact lenses: hilafilcon B hydrogel versus narafilcon A silicone hydrogel

Saraç¹,

Gürdal²,

Bostancı-Ceran³

et al. 2012

Int Ophthalmol

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“…Tear volume is distributed across three continuous compartments: the cul-de-sac, the conjunctival tear menisci, and the preocular tear film, and it depends on the rates of tear production, drainage, and evaporation. It has been reported that tear meniscus variables, such as height, width, cross-sectional area, and meniscus curvature are useful for the diagnosis of dry eye [13][14][15][16][17][18][19]. It is reasonable to use lower tear meniscus parameters as objective indicators of tearfilm status, since Wang et al [20] showed that upper and lower tear menisci have almost identical volume in healthy eyes.…”

Section: Introductionmentioning

confidence: 97%

Assessment of corneal thickness and tear meniscus during contact-lens wear

Águila-Carrasco

Ferrer-Blasco

García‐Lázaro

et al. 2015

Contact Lens and Anterior Eye

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“…Generally more than one objective test is needed to diagnose the condition, and to date there is no rigorous standard series of tests for clinicians to follow. For example, the phenol red thread (PRT) test is an index of tear production [8][9][10] , while tear break-up time assesses the stability of the tear film [8,10] . The large variety of available tests has led to widespread differences in the diagnosis of dry eye and the prevalence of their use in clinical practice, as revealed by a web-based questionnaire [11] .…”

Section: Introductionmentioning

confidence: 99%

Attitudes towards Diagnostic Tests and Therapies for Dry Eye Disease

et al. 2009

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Aim: The purpose of this study was to survey the attitudes of optometrists and ophthalmologists, located in a number of different countries, towards diagnostic tests and therapies for dry eye disease. Methods: A web-based questionnaire was used to survey attitudes using forced-choice questions and Likert scales. Results: Sixty-one respondents (23 ophthalmologists and 38 optometrists) reported a wide range of patient dry eye symptoms. A large variation in use of diagnostic tests was noted. Patient symptoms and fluorescein staining were reported to be significantly more valuable and more frequently performed than any other test. Artificial tear supplements and improved lid hygiene were the preferred therapeutic options selected by the entire group. The results demonstrated a wide variation in attitudes in relation to satisfaction with the range of available diagnostic and therapeutic options. Conclusions: This study indicates that the interest for the issue of dry eye is relatively limited amongst eye professionals, as demonstrated by the poor participation in the questionnaire.

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A Comparison of Tear Volume (by Tear Meniscus Height and Phenol Red Thread Test) and Tear Fluid Osmolality Measures in Non-Lens Wearers and in Contact Lens Wearers

Abstract: Even contemporary contact lens wear can have a small but measurable impact on the precorneal tear film osmolality or volume. The changes are internally consistent and, overall, support the idea that the PRT test provides a useful measure of tear meniscus volume.

Cited by 80 publications

References 20 publications

Comparison of tear osmolarity and ocular comfort between daily disposable contact lenses: hilafilcon B hydrogel versus narafilcon A silicone hydrogel

Comparison of tear osmolarity and ocular comfort between daily disposable contact lenses: hilafilcon B hydrogel versus narafilcon A silicone hydrogel

Assessment of corneal thickness and tear meniscus during contact-lens wear

Attitudes towards Diagnostic Tests and Therapies for Dry Eye Disease

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