A comparison of the clinical effects associated with xylazine, ketamine, and a xylazine-ketamine cocktail in pigeons (Columba livia)

Durrani, Uzma Farid; Ashraf, Muhammad; Khan, Muhammad Arif

doi:10.3906/vet-0805-7

Cited by 9 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in accordance with the study done by Steinbacher, (2001). The pronounced decrease in respiratory rate with xylazine-ketamine combination is also in agreement with the study done by Gandomani et al (2011) and Uzma et al (2009). Xylazine has a high depressant action on the respiratory system (Uzma et al, 2009).…”

Section: Discussionsupporting

confidence: 91%

“…The pronounced decrease in respiratory rate with xylazine-ketamine combination is also in agreement with the study done by Gandomani et al (2011) and Uzma et al (2009). Xylazine has a high depressant action on the respiratory system (Uzma et al, 2009). Thiopental causes respiratory depression and in combination with xylazine caused a more pronounced decrease in the respiratory rate (Kumar 2012).…”

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Comparative evaluation of the effect of thiopental, propofol, and ketamine anaesthesia during experimental surgical wound repair in xylazine premedicated local chicken

2023

JoSVAS

View full text Add to dashboard Cite

This study determined the suitable general anaesthetic regimen in local chicken that underwent experimental wound repair by comparing the effect of different anaesthetic protocols. Fifteen healthy matured layer local chickens of average weight of 0.2kg were used for the study. They were randomly assigned into three groups (A–C) of five birds each. Birds in all groups were premedicated with xylazine 2 mg/kg body weight (b/w) IV. Birds in groups A, B and C were anaesthetized with thiopentone, 30 mg/kg (b/w), propofol, 15 mg/kg (b/w) and ketamine, 25 mg/kg (b/w) respectively through the jugular vein. Surgical incisions were made on breast muscle at the depth of 0.1cm and length of 2cm and sutured using size 1 chromic catgut and size 3/0 silk for muscles and skin respectively. The physiological parameters were recorded at 0 min pre induction and subsequently every ten (10) min interval post induction. The anaesthetic indices were also recorded. Data were compared using analysis of variance (ANOVA). The result showed that propofol-xylazine had significantly (𝑃 ≤ 0.05) faster onset, short duration of recumbency, minimal effect on the cardiopulmonary system and on the blood glucose, but provide short surgical anaesthetic time when compared to other drugs. Thiopental-xylazine significantly (𝑃 ≤ 0.05) caused more cardiopulmonary depression compare to Ketamine-xylazine. Ketamine-xylazine had significantly (𝑃 ≤ 0.05) longest onset, duration of recumbency and surgical anaesthetic time with stable cardiopulmonary function among the drugs. Ketamine-xylazine regimen may be considered as the best of the three anaesthetics protocol in local chicken especially during long surgical procedure.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%

Comparative evaluation of the effect of thiopental, propofol, and ketamine anaesthesia during experimental surgical wound repair in xylazine premedicated local chicken

2023

JoSVAS

View full text Add to dashboard Cite

show abstract

“…It has been argued that these agents lead to bradycardia and respiratory depression and provide inadequate sedation, and therefore, they should be used only for holding and procedures involving little pain. The same researchers have also emphasized that α 2 agonists used alone lead to time-dependent hypothermia (Duranni et al, 2008;Duranni et al, 2009;Pollock et al, 2001;Sandmeier, 2000). The findings obtained in this study were consistent with the results of the researchers who have stated that pigeons are relatively resistant to α 2 adrenergic agonists (Duranni et al, 2008;Duranni et al, 2009;Pollock et al, 2001;Sandmeier, 2000).…”

Section: Discussionsupporting

confidence: 90%

“…The same researchers have also emphasized that α 2 agonists used alone lead to time-dependent hypothermia (Duranni et al, 2008;Duranni et al, 2009;Pollock et al, 2001;Sandmeier, 2000). The findings obtained in this study were consistent with the results of the researchers who have stated that pigeons are relatively resistant to α 2 adrenergic agonists (Duranni et al, 2008;Duranni et al, 2009;Pollock et al, 2001;Sandmeier, 2000). Additionally, studies conducted on medetomidine showed that the dosage used in this study was low, and medetomidine could be researched at higher dosages (Pollock et al, 2001;Sandmeier, 2000).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Anesthetic Properties of Dexmedetomidine and Dexmedetomidine-Ketamine Combination and the Properties of Atipamezole as a Reversal Agent in Domestic Pigeons

Ağış,

Yavuz

2024

Erciyes Üniversitesi Veteriner Fakültesi Dergisi

View full text Add to dashboard Cite

The aim of this study was to determine the anesthetic efficacy of dexmedetomidine and ketamine alone and dexmedetomidine-ketamine combination and the effects of α2 adrenergic reversal atipamezole in domestic pigeons (Columba livia). In DX group, dexmedetomidine (80 μg/kg), in K group, ketamine (100 mg/kg) alone, in DXK group, dexmedetomidine (40 μg/kg) and ketamine (50 mg/kg) consecutively were administered intramuscularly (IM). Anesthetic depth and cardiopulmonary symptoms were monitored starting from the pre-injection moment (T0) till the 60th minute (T60). At T60, atipamezole at a dosage 4 times that of dexmedetomidine was injected intramuscularly to the DX group (320 μg/kg) and the DXK group (160 μg/kg). In the DX group, only minimal sedation, bradycardia, and a sudden drop in respiratory rate were seen (P

show abstract

“…Xylazine is also used to initiate and prolong the duration of the general anesthesia, in addition showing the myorelaxant, sedative and analgesic effect at the time used as a premedicant [3,8,9]. The combination of xylazine hydrochloride with ketamine hydrochloride may be producing an easy induction with cataleptic state of recovery [8,10]. The popularity of ketamine-xylazine (KX) combination is used mainly because of its supplemental effects (that is, muscle relaxation, analgesic properties, and sedation) [8,11].…”

Section: Introductionmentioning

confidence: 99%

Comparative Study Between IV and IM Co-administration of Xylazine with Ketamine on Some Physiological Parameters in Dogs

hasan,

S. M. Alnajjar

2023

Egyptian Journal of Veterinary Sciences

View full text Add to dashboard Cite

C LINICAL anesthetic trial was conducted on 12 local dogs in different age, sex and body weight. The aim of study is to investigate the compatartive effect of ketamine and xylazine combination injected either IM or IV on the anetshetic (induction times, duration of anesthesia and recovery time) and physiological parameters on the dogs. They were divided into two groups (G-I and G-II) randomly. All dogs were administered with atropine sulphate (0.04mg\kg BW, IM) 5 minutes before anesthetic protocol, ketamine+xylazine (10mg\kg+1mg\kg) respectively, was adminstered IM in G-I and IV in G-II. Clinical findings including inductions, duration and recovery period of anestehsia, HR, RR, RT, SPO2, SBP, DBP and MAP were recorded before and during anesthesia. The study show that there were no significant differences between G-I and G-II in physiological parameters of ketamine and xylazine anethesia in dogs except induction, duration and recovery of anesthesia was longer in G-I than G-II. In conclusion, the results demonstrated that the combination of ketamine+xylazine can be a special satisfatcory anesthetic protocol for excellent induction, good muscle relaxant and smooth recovery in dogs.

show abstract

A comparison of the clinical effects associated with xylazine, ketamine, and a xylazine-ketamine cocktail in pigeons (Columba livia)

Cited by 9 publications

References 9 publications

Comparative evaluation of the effect of thiopental, propofol, and ketamine anaesthesia during experimental surgical wound repair in xylazine premedicated local chicken

Comparative evaluation of the effect of thiopental, propofol, and ketamine anaesthesia during experimental surgical wound repair in xylazine premedicated local chicken

Evaluation of the Anesthetic Properties of Dexmedetomidine and Dexmedetomidine-Ketamine Combination and the Properties of Atipamezole as a Reversal Agent in Domestic Pigeons

Comparative Study Between IV and IM Co-administration of Xylazine with Ketamine on Some Physiological Parameters in Dogs

Contact Info

Product

Resources

About