A comparison of the effectiveness of oxytetracycline or salt water in the management of digital dermatitis in dairy cattle

R., Ishmael; Goodman, T.; Martin, Jaime H.; Stockwell, C.

doi:10.1017/s1752756200011182

Cited by 2 publications

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“…The length of the studies (period of CT administration and follow-up) ranged from 2 to 24 wk. Only 4 studies performed multiple-outcomes observations during the follow-up period (Ishmael et al, 2005;Speijers et al, 2010;Relun et al, 2012Relun et al, , 2013a. The preventive crossover trial included in the review (Klaas et al, 2008) did not have a washout period; therefore, only information on the first period of this study was considered for each group of animals as a trial.…”

Section: Search Results and Study Selectionmentioning

confidence: 99%

“…Case and success definitions, proportions of outcome events (occurrence rates and healing rates), and the OR (95% CI) associated with each study are reported in Tables 2 and 3, according to the prevention or treatment outcomes. For 4 studies, data on the results of the trials' effectiveness were unclear in the publication, and it was therefore impossible to calculate the proportion of outcome events and the OR (Fiedler, 2004;Ishmael et al, 2005;Bergsten et al, 2006;Rasmussen et al, 2011). Among the prevention trial comparisons, 17 products were tested involving different disinfectants; 9 of these relied on copper bactericidal properties, 2 on glutaraldehyde, 2 on organic acids, 1 on sodium hypochlorite, 1 on NaCl, 1 on quaternary ammonium, and 1 on calcium hydroxide.…”

Section: Study Characteristicsmentioning

confidence: 99%

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Effectiveness of collective treatments in the prevention and treatment of bovine digital dermatitis lesions: A systematic review

Ariza

Relun

Bareille

et al. 2017

Journal of Dairy Science

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The collective treatment (CT) of an affected herd is commonly advised to control bovine digital dermatitis (DD). Several CT are commercialized, frequently without major evidence supporting their effectiveness. The objective of this systematic review was to evaluate the published evidence that supports CT in the treatment and prevention of DD lesions in dairy herds. Across the evidence, the main limitations in the studies design were identified and the possible sources of inconsistency were investigated. An extensive literature search of publications through electronic databases and gray literature was conducted between July 2015 and January 2016. Studies that did not include an untreated or placebo control group were excluded from the review. The literature search and screening process identified 13 publications with 24 treatment trial comparisons and 18 prevention trial comparisons. The published evidence included studies mostly considered to have a low or unclear risk of bias. Descriptive analyses were performed according to the prevention and treatment outcomes, and case and success definitions were identified for each study and summarized in odds ratios (OR). Pairwise meta-analyses were conducted according to the prevention and treatment outcomes, comparing directly the intervention used in each study, and ignoring any other differences in the intervention characteristics. The results of the meta-analyses indicated a low degree of heterogeneity across the evidence for the prevention outcome [I = 0%, 95% CI: 0 to 37.2%, 95% prediction interval (PI): 0.72 to 1.74)] and a moderate degree for the treatment outcome (I = 25.3%, 95% CI: 0 to 63%, 95% PI: 0.39 to 3.73). Similarly, appraisal of the graphical L'Abbé plot suggested a considerable degree of heterogeneity across the evidence for the treatment outcome. For both outcomes, the frequent small sample sizes of the trials indicate imprecision across the included studies. Additionally, for the treatment and prevention outcomes, an asymmetric funnel plot suggested possible publication bias. The overall quality of the evidence, for both outcomes (prevention and treatment), was therefore considered to be low, indicating that the true effect of CT may be substantially different from that estimated across the included studies. Consequently, this review and meta-analysis does not support an association between the CT considered in the review and a beneficial effect in the prevention and treatment of DD lesions. The effectiveness of CT therefore remains uncertain, and the epidemiological circumstances in which it can be useful must be investigated. These findings highlight the importance of developing high quality, controlled trials to evaluate the effectiveness of CT for DD control.

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Section: Search Results and Study Selectionmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Effectiveness of collective treatments in the prevention and treatment of bovine digital dermatitis lesions: A systematic review

Ariza

Relun

Bareille

et al. 2017

Journal of Dairy Science

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“…It was suggested that salt water, when used as a topical spray, could provide a cost-effective alternative to antibiotic use on farms as a preventative measure against DD (Ishmael et al, 2005). Salt is a common household antiseptic treatment that kills bacteria by dehydration (Matin et al, 2006).…”

Section: Figurementioning

confidence: 99%

Effectiveness of different footbath solutions in the treatment of digital dermatitis in dairy cows

Speijers

Baird

Finney

et al. 2010

Journal of Dairy Science

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Three experiments were conducted to test the effectiveness of different footbath solutions and regimens in the treatment of digital dermatitis (DD) in dairy cows. During the study, groups of cows walked through allocated footbath solutions after milking on 4 consecutive occasions. All cows were scored weekly for DD lesion stage on the hind feet during milking. A "transition grade" was assigned on the basis of whether the DD lesions improved (1) or deteriorated or did not improve (0) from week to week. This grade per cow was averaged for all cows in the group. In experiment 1, 118 cows were allocated to 1 of 3 footbath treatments for 5 wk: (1) 5% CuSO(4) each week, (2) 2% ClO(-) each week, or (3) no footbath (control). The mean transition grade, and proportion of cows without DD lesions at the end of the trial were significantly higher for treatment 1 above (0.36, 0.13, and 0.11, respectively; standard error of the difference, SED = 0.057). In experiment 2, 117 cows were allocated to 1 of 4 footbath treatment regimens for 8 wk: (1) 5% CuSO(4) each week, (2) 2% CuSO(4) each week, (3) 5% CuSO(4) each fortnight, or (4) 2% CuSO(4) each fortnight. For welfare reasons, cows allocated to the weekly and fortnightly footbath regimens had an average prevalence of >60% and ≤25% active DD at the start of the trial, respectively. Significantly more cows had no DD lesions (0.53 vs. 0.36, respectively; SED = 0.049), and the mean transition grade of DD lesions was higher in the 5% compared with the 2% weekly CuSO(4) treatment (0.52 vs. 0.38, respectively; SED = 0.066). Similarly, significantly more cows had no DD lesions in the 5% compared with the 2% fortnightly CuSO(4) treatments (0.64 vs. 0.47, respectively; SED = 0.049). In experiment 3, 95 cows were allocated to 1 of 3 footbath treatments: (1) each week alternating 5% CuSO(4) with 10% salt water, (2) each week alternating 5% CuSO(4) with water, or (3) 5% CuSO(4) each fortnight (control). After 10 wk, more cows had no DD in the salt water treatment than in the control treatment (0.35 vs. 0.26, respectively; SED = 0.038), but levels of active lesions were higher for this treatment than in the other 2 treatments (0.17, 0.00, and 0.13, respectively; SED = 0.029). Treatment did not affect mean transition grade of DD lesions. In conclusion, CuSO(4) was the only footbath solution that was consistently effective for treatment of DD. In cases when DD prevalence was high, a footbath each week using 5% CuSO(4) was the most effective treatment.

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A comparison of the effectiveness of oxytetracycline or salt water in the management of digital dermatitis in dairy cattle

Cited by 2 publications

References 0 publications

Effectiveness of collective treatments in the prevention and treatment of bovine digital dermatitis lesions: A systematic review

Effectiveness of collective treatments in the prevention and treatment of bovine digital dermatitis lesions: A systematic review

Effectiveness of different footbath solutions in the treatment of digital dermatitis in dairy cows

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