“…As for peritonitis, concerns have been raised that the creation of capnoperitoneum in patients with established peritonitis may be detrimental with respect to potentiation of bacteremia, endotoxemia, and severe sepsis/ Experimental studies have yielded conflicting data in this regard. In animal models of peritonitis, endotoxemia, and the development of intra-abdominal abscesses do not seem to be increased by CO 2 laparoscopy when compared with control groups [15,42]. Over the past few years there have been increasing numbers of series reporting favorable results on the use of laparoscopy in the treatment of peritonitis [3,4,12,13,18,20,21,23,29,34,41,43].…”