A comparison of the hemodynamic and ventilatory effects of abdominal insufflation with helium and carbon dioxide in young swine

Liem, Timothy K.; Krishnamoorthy, Mohan; Applebaum, Harry; Kolata, Ronald J.; Rudd, Ray; Chen, Wansu

doi:10.1016/s0022-3468(96)90020-2

Cited by 16 publications

(8 citation statements)

References 14 publications

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“…Adhesion formation was higher in animals poorly ventilated and decreased with higher ventilation rates. In comparison with animals that underwent anaesthesia only, the CO 2 -induced pneumoperitoneum increases the pCO 2 and decreases the pH, as has been reported in animal models [ 31 , 34 , 155 ] and humans [ 36 ]. These effects were more pronounced in poorly ventilated mice and counteracted by appropriate ventilation (i.e.…”

Section: General Impact Of the Standard Co 2 -Indumentioning

confidence: 60%

Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery

Binda

2015

Arch Gynecol Obstet

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PurposeThe peritoneum is the serous membrane that covers the abdominal cavity and most of the intra-abdominal organs. It is a very delicate layer highly susceptible to damage and it is not designed to cope with variable conditions such as the dry and cold carbon dioxide (CO2) during laparoscopic surgery. The aim of this review was to evaluate the effects caused by insufflating dry and cold gas into the abdominal cavity after laparoscopic surgery.MethodsA literature search using the Pubmed was carried out. Articles identified focused on the key issues of laparoscopy, peritoneum, morphology, pneumoperitoneum, humidity, body temperature, pain, recovery time, post-operative adhesions and lens fogging.ResultsInsufflating dry and cold CO2 into the abdomen causes peritoneal damage, post-operative pain, hypothermia and post-operative adhesions. Using humidified and warm gas prevents pain after surgery. With regard to hypothermia due to desiccation, it can be fully prevented using humidified and warm gas. Results relating to the patient recovery are still controversial.ConclusionsThe use of humidified and warm insufflation gas offers a significant clinical benefit to the patient, creating a more physiologic peritoneal environment and reducing the post-operative pain and hypothermia. In animal models, although humidified and warm gas reduces post-operative adhesions, humidified gas at 32 °C reduced them even more. It is clear that humidified gas should be used during laparoscopic surgery; however, a question remains unanswered: to achieve even greater clinical benefit to the patient, at what temperature should the humidified gas be when insufflated into the abdomen? More clinical trials should be performed to resolve this query.

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Section: General Impact Of the Standard Co 2 -Indumentioning

confidence: 60%

Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery

Binda

2015

Arch Gynecol Obstet

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“…Various hemodynamic patterns have been described. Decreases [12,15], increases [2,8], as well as no alterations [9,14,16,19,21] in MAP during pneumoperitoneum have been reported. These con¯ict-ing results may be due to dierences in intravascular volume status, the level of intraabdominal pressure, the level of CO 2 in the blood, anesthetic regimen, and lack of adequate statistical power.…”

Section: Discussionmentioning

confidence: 92%

Impact of carbon dioxide and helium insufflation on cardiorespiratory function during prolonged pneumoperitoneum in an experimental rat model

et al. 2002

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“…Hemodynamic, respiratory, endocrine, and metabolic responses to abdominal insufflation with helium have been extensively evaluated in both laboratory animal [6,10,11,13,20,24] and human clinical studies [8,15,18,19]. Helium has been recognized as an alternative gas for insufflation and may be the agent of choice in high-risk patients with significant cardiopulmonary disease [8,15,19].…”

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confidence: 99%

Videoscopic surgery under local and regional anesthesia with helium abdominal insufflation

Crabtree

Fishman

1999

Surg Endosc

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Helium gas should be considered the agent of choice for intraperitoneal insufflation in high-risk patients not only because helium avoids the metabolic consequences of CO(2) insufflation but also because it permits selected procedures to be performed under local-regional anesthesia. Helium may be contraindicated for laparoscopic procedures involving extraperitoneal insufflation due to the increased risk for pneumothoraces.

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A comparison of the hemodynamic and ventilatory effects of abdominal insufflation with helium and carbon dioxide in young swine

Cited by 16 publications

References 14 publications

Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery

Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery

Impact of carbon dioxide and helium insufflation on cardiorespiratory function during prolonged pneumoperitoneum in an experimental rat model

Videoscopic surgery under local and regional anesthesia with helium abdominal insufflation

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