A comparison of the HLA database of the Romanian population with the Balkan populations

Matei, Luminita; Panaitescu, Eugenia; Dogaroiu, Catalin

doi:10.4323/rjlm.2012.223

Cited by 6 publications

(3 citation statements)

References 4 publications

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“…Although the prevalence of Behcet's disease in UAE Arabs, and particularly the Bedouin, is not known, it has been associated strongly with HLA‐B*51 in the population of Turkey, Israel, Iran, Saudi Arabia, Iraq and Japan, and those along the historic Silk Road (Keino & Okada, ). HLA‐B*50 , the other high‐frequency HLA‐B allele in the UAE (Table ) and Saudi Arabia (Hajeer et al, ), is relatively low (<0.05) in the Turkish and Balkan populations (Matei, Panaitescu, & Dogaroiu, ), but has been associated strongly with conversion to Myasthenia Gravis after ocular onset in the Turkish population (Tiftikcioglu et al, ).…”

Section: Resultsmentioning

confidence: 99%

HLA class I allele lineages and haplotype frequencies in Arabs of the United Arab Emirates

Kulski

Alsafar

Mawart

et al. 2019

Int J Immunogenetics

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The high degree of polymorphism of the HLA system provides suitable genetic markers to study the diversity and migration of different world populations and is beneficial for forensic identification, anthropology, transplantation and disease associations. Although the United Arab Emirates (UAE) population of about nine million people is heterogeneous, information is limited for the HLA class I allele and haplotype frequencies of the Bedouin ethnic group. We performed low‐resolution PCR‐SSP genotyping of three HLA class I loci at HLA‐A, ‐B and ‐C for 95 unrelated healthy Bedouins from the cities of Al Ain and Abu Dhabi in the UAE. A total of 54 HLA allele lineages were detected; the most frequent low‐resolution allele lineages at each HLA locus were A*02 (0.268), B*51 (0.163) and C*07 (0.216). The inferred estimates for the two most frequent HLA‐A and HLA‐B haplotypes were HLA‐A*02 ~ HLA‐B*50 (0.070) and HLA‐A*02 ~ HLA‐B*51 (0.051), and the most frequent 3‐locus haplotype was HLA‐A*02 ~ HLA‐B*50 ~ HLA‐C*06 (0.068). The HLA allele lineage frequencies of the UAE Arabs were compared to those previously reported for 70 other world populations, and a strong genetic similarity was detected between the UAE Arabs and the Saudi Arabians from the west with evidence of a limited gene flow between the UAE Arabs and Pakistani across the Gulf from the east, and the UAE Arabs and Omani from the south of the Gulf Peninsula.

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Section: Resultsmentioning

confidence: 99%

HLA class I allele lineages and haplotype frequencies in Arabs of the United Arab Emirates

Kulski

Alsafar

Mawart

et al. 2019

Int J Immunogenetics

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“…Bisphenol A is widely used in the fabrication of epoxy resin can liners, polycarbonate plastics, medical equipment, dental sealants, and heat transfer papers [3,5,22,[33][34][35]. It has a dual mechanism of action, exerting both pro-and anti-estrogenic effects depending on tissue [35].…”

Section: Bisphenol a (Bpa)mentioning

confidence: 99%

The Impact of Endocrine-Disrupting Chemicals on Female Fertility

Petca¹,

Măru²,

Dumitrașcu³

et al. 2020

Rev. Chim.

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Nowadays, infertility is a prevalent problem among couples. Exposure to endocrine-disrupting chemicals (EDCs) may influence the female reproductive outcomes through multiple mechanisms, being one of the important causes of infertility. These compounds may interfere with some fertility and fecundity markers, leading to increased time to pregnancy, increased risk of spontaneous abortion, shorter menstrual cycles, early age at menopause, anovulation or delayed ovulation, smaller preovulatory follicles, increased serum FSH, decreased synthesis of estradiol and progesterone, low plasma levels of anti-Mullerian hormone and decreased antral follicle count. Endocrine-disrupting chemicals may also impair in vitro fertilization outcomes, being responsible for: a lower probability of implantation, reduced fertilization rates, diminished probability of clinical pregnancy, and near term pregnancies after in vitro fertilization. Another mechanism of altering the female reproductive function is through the disorders induced by EDCs, such as polycystic ovary syndrome, uterine fibroids, and endometriosis. Those conditions may finally lead to infertility.

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“…This conditions lead to precipitation of uric acid. The clinical picture associated with this type of lithiasis is usually with high BMI, glucose intolerance and type 2 diabetes [13][14][15].…”

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confidence: 99%

Could Chemical Composition of Stone Influence Percutaneous Nephrolithotomy in the Management of Staghorn Calculi?

Petca¹,

Salaheddin²,

Petca³

et al. 2019

Rev.Chim.

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The management of large renal stones is a challenging situation for the urologists. PCNL (percutaneous nephrolithotomy) represents the elective procedure and can be performed as monotherapy or combined with other techniques. This is a retrospective study on 75 patients diagnosed with staghorn calculi at Prof. Dr. Th. Burghele Clinical Hospital who underwent PCNL between 01.01.2018 to 31.06.2018. The aim of this study is to evaluate the correlations between the staghorn chemical composition, the stone free rate and the complication rate after surgery according to modified Clavien Dindo system of evaluation for urological procedures.

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A comparison of the HLA database of the Romanian population with the Balkan populations

Cited by 6 publications

References 4 publications

HLA class I allele lineages and haplotype frequencies in Arabs of the United Arab Emirates

HLA class I allele lineages and haplotype frequencies in Arabs of the United Arab Emirates

The Impact of Endocrine-Disrupting Chemicals on Female Fertility

Could Chemical Composition of Stone Influence Percutaneous Nephrolithotomy in the Management of Staghorn Calculi?

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