A Comparison of Tramadol, Amitriptyline, and Meperidine for Postepidural Anesthetic Shivering in Parturients

Tsai, Yu Chuan; Chu, Koung Shing

doi:10.1097/00000539-200111000-00052

Cited by 144 publications

(142 citation statements)

References 26 publications

Supporting

Mentioning

119

Contrasting

Unclassified

Order By: Relevance

“…It also modulates the activity of nucleus median raphe acting centrally on the m opioid receptors predominately with minimum effects on k and d receptors. The antishivering effect of tramadol is mediated via serotonergic of noradrenertic receptor or both [10][11][12]. Tramadol in a dose of 1mg/ kg iv has been shown to be effective in the treatment of postoperative shivering.…”

Section: Discussionmentioning

confidence: 99%

A Randomised Trial Comparing Efficacy, Onset and Duration of Action of Pethidine and Tramadol in Abolition of Shivering in the Intra Operative Period

Kaparti

2014

JCDR

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

A Randomised Trial Comparing Efficacy, Onset and Duration of Action of Pethidine and Tramadol in Abolition of Shivering in the Intra Operative Period

Kaparti

2014

JCDR

View full text Add to dashboard Cite

“…Mean arterial blood pressure and heart rates were recorded every 15 minutes with noninvasive blood pressure monitoring and pulse oximetry. Shivering involving whole body was checked every 5 minutes during surgery and at recovery room by a 4 point rating score system (0: none, 1: mild fasciculation in face or neck, 2: visible tremor in more than one muscle group, 3: shivering involving whole body) for 2 hours [6,7,19,20] . In case of shivering score ≥ 2 intravenous pethidine 0.5 mg/kg was given.…”

Section: Methodsmentioning

confidence: 99%

“…It increases oxygen consumption, lactic acidosis, carbon dioxide production and catecholamine release [4][5][6][7] . One of the primary causes of post anesthesia shivering (PAS) is hypothermia which is due to direct inhibition of body thermoregulatory mechanisms by anesthetics, decreased metabolism, patient's exposure to cold environment of operating rooms and body cavity exposure of postoperative shivering [11] .…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of Three Different Doses of Intrathecal Fentanyl for Prevention of Shivering in Lower Limb Orthopedic Surgeries: A Randomized Double-Blind Controlled Trial

Safavi¹

2016

JAS

View full text Add to dashboard Cite

. Shivering, along with pain, nausea and vomiting are cases of discomfort and dissatisfaction in patients undergoing spinal anesthesia [9] . The combination of lipophilic opioids with hyperbaric bupivacaine during spinal anesthesia provides reduced latency, longer duration of anesthesia and better quality of anesthesia [10] . Another known effect of intrathecal opioids is prevention and treatment AbstractBackground: Fentanyl has been used to prevent shivering in spinal anesthesia but still the effects of different doses have not been appropriately specified. The aim of this study was to assess the effect of 10 µg, 20 µg and 30 µg intrathecal fentanyl on prevention of shivering during and after lower limb orthopedic surgeries under spinal anesthesia. Materials and Methods:One hundred and twenty patients undergoing elective orthopedic surgery under spinal anesthesia were enrolled in this clinical trial. Subjects were randomly divided to four groups; Group P received 3 cc bupivacaine 0.5% plus normal saline intrathecally; Group A10 received 10 µg fentanyl plus 3 cc bupivacaine 0.5% intrathecally; Group B20 received 20 μg fentanyl plus 3 cc bupivacaine 0.5% intrathecally; and Group C30 received 30 μg fentanyl plus 3 cc bupivacaine 0.5% intrathecally. Shivering and the complications were recorded. Results: Shivering intensity was different between 4 groups (P = 0.014). There was no moderate, severe and very severe shivering seen in Group C30 but there was 16.7% moderate, 10% sever, and 6.7% very severe shivering seen in Group P. The total incidence of shivering after spinal anesthesia in Groups A10, Group B20, Group C30 and Group P were 53.5%, 26.7% , 6.7% and 63.3% respectively and there was statistically significant difference between 4 group in this regard (P < 0.001). Conclusion: Intrathecal bupivacaine combined with 30 μg fentanyl was superior to using 10 µg or 20 μg fentanyl for prevention of shivering during lower extremity orthopedic surgery.

show abstract

“…Em estudo realizado em 220 pacientes com o objetivo de identificar a dose eficaz de meperidina para o tratamento de tremores, Crossley 76 concluiu que 0,35 mg.kg -1 é a menor quantidade necessária para tratar tremor pós-operató-rio de forma satisfatória. O uso do tramadol para tratamento de tremores tem sido feito nos últimos anos, e a sua eficácia é semelhante à da meperidina segundo alguns estudos 77 . O nefopam é uma benzoxacina analgésica de ação central que reduz os tremores sem comprometer a ventilação, com mínimos efeitos sedativos e com eficiência comprovada.…”

Section: Tratamento Dos Tremores Pós-operatóriosunclassified

“…In a study with 220 patients aiming at identifying the effective dose of meperidine for the treatment of tremors, Crossley 76 concluded that 0.35 mg.kg -1 is the smallest dose necessary to treat adequately postoperative tremors. Tramadol has also been used in the past few years to treat tremors and, according to some studies, its efficacy is similar to that of meperidine 77 . Nefopam is a central-acting analgesic benzoxacin that reduces tremors without affecting ventilation, with minimal sedation, and proven efficacy.…”

Section: Treatment Of Postoperative Tremorsmentioning

confidence: 99%

Tremores intra e pós-operatório: prevenção e tratamento farmacológico

Albergaria

Lorentz²,

Lima³

2007

Rev. Bras. Anestesiol.

View full text Add to dashboard Cite

RESUMOAlbergaria VF, Lorentz MN, Lima FAS -Tremores Intra e Pós-Operatório: Prevenção e Tratamento Farmacológico. JUSTIFICATIVA E OBJETIVOS:Os tremores podem ocorrer como um efeito adverso da intervenção cirúrgica e anestesia. A incidência de tremores pós-operatórios varia entre 6,3% e 66%. Pacientes jovens, sexo masculino, uso de agentes anestésicos halogenados e tempo prolongado de anestesia ou procedimento cirúrgico estão relacionados com tremores. Os tremores são involuntários e apresentam-se como atividade muscular oscilatória com finalidade de aumentar a produção de calor. Tremor pós-operatório é uma desagradável complicação que está relacionada com o aumento de morbidade. O tremor aumenta o metabolismo, resultando em um acréscimo de 200% a 500% no consumo de oxigênio. CONTEÚDO:Discute as causas, a prevenção e o tratamento dos tremores intra-e pós-operatório em pacientes adultos e pediátri-cos submetidos à intervenção cirúrgica sob anestesia geral ou do neuroeixo. CONCLUSÕES:Os tremores são, juntamente com náuseas e vô-mitos, causas de intenso desconforto na sala de recuperação pós-anestésica, além de potencialmente prejudiciais por gerarem aumento da demanda metabólica. Embora a presença de tremores não tenha sido diretamente relacionada com a morbidade cardía-ca, a prevenção tem se tornado tema de debate e de vários artigos científicos. A prevenção e o tratamento de tremores devem ser implementados. Pacientes com reserva cardiopulmorar limitada podem sofrer com acidose láctica, dessaturação venosa mista e hipoxemia.Unitermos: ANESTESIA: Geral, Locorregional; COMPLICAÇÕES: hipotermia, tremor; TREMOR: prevenção, tratamento. SUMMARYAlbergaria VF, Lorentz MN, Lima FAS -Intra-and Postoperative Tremors: Prevention and Pharmacological Treatment. BACKGROUND AND OBJECTIVES:Tremors can be an adverse effect of the surgical intervention and anesthesia. The incidence of postoperative tremors varies from 6.3% to 66%. Young age, male gender, the use of halogenated anesthetics, and prolonged anesthesia or surgical procedure are related with tremors. Tremors are involuntary and present as oscillating muscular activity aiming at increasing heat production. Postoperative tremors are a disagreeable complication related with increased morbidity. Tremors increase the metabolism, resulting in a 200% to 500% increase in oxygen consumption. CONTENTS:The objective of this paper was to discuss the causes, prevention, and treatment of intra-and postoperative tremors in adults and children undergoing general anesthesia or neuroaxis anesthesia for surgical interventions. CONCLUSIONS:Tremors, along with nausea and vomiting, cause severe discomfort in the recovery room, besides being highly prejudicial because they generate an increase in the metabolism. Although the presence of tremors has not been directly related with cardiac morbidity, its prevention has become the subject of discussion and several scientific reports. Prevention and treatment of tremors should be implemented. Patients with limited cardiovascular reserve could devel...

show abstract

A Comparison of Tramadol, Amitriptyline, and Meperidine for Postepidural Anesthetic Shivering in Parturients

Cited by 144 publications

References 26 publications

A Randomised Trial Comparing Efficacy, Onset and Duration of Action of Pethidine and Tramadol in Abolition of Shivering in the Intra Operative Period

A Randomised Trial Comparing Efficacy, Onset and Duration of Action of Pethidine and Tramadol in Abolition of Shivering in the Intra Operative Period

The Efficacy of Three Different Doses of Intrathecal Fentanyl for Prevention of Shivering in Lower Limb Orthopedic Surgeries: A Randomized Double-Blind Controlled Trial

Tremores intra e pós-operatório: prevenção e tratamento farmacológico

Contact Info

Product

Resources

About