A Comparison of Trauma Profiles among Individuals with Prescription Opioid, Nicotine, or Cocaine Dependence

Lawson, Katie M.; Back, Sudie E.; Hartwell, Karen J.; Maria, Megan Moran-Santa; Brady, Kathleen T.

doi:10.1111/j.1521-0391.2013.00319.x

Cited by 79 publications

(55 citation statements)

References 22 publications

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“…A history of physical and sexual abuse and resultant PTSD is a risk factor for substance abuse (Cottler, Compton, Mager, Spitznagel, & Janca, 1992; Greenfield et al, 2010; Lawson, Back, Hartwell, Moran-Santa Maria, & Brady, 2013). In addition, co-morbidity of substance abuse and other psychiatric disorders including depression, anxiety, conduct disorder or ADHD is common (Charach, Yeung, Climans, & Lillie, 2011; Compton, Thomas, Stinson, & Grant, 2007; Flory & Lynam, 2003; Goldstein et al, 2007; Hasin, Stinson, Ogburn, & Grant, 2007).…”

Section: Sex Differences In Intrinsic and Extrinsic Factors Contrimentioning

confidence: 99%

Emergence of sex differences in the development of substance use and abuse during adolescence

Kuhn

2015

Pharmacology & Therapeutics

148

109

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Substance use and abuse begins during adolescence. Male and female adolescent humans initiate use at comparable rates, but males increase use faster. In adulthood, more men than women use and abuse addictive drugs. However, some women progress more rapidly from initiation of use to entry into treatment. In animal models, adolescent males and females consume addictive drugs similarly. However, reproductively mature females acquire self-administration faster, and in some models, escalate use more. Sex/gender differences exist in neurobiologic factors mediating both reinforcement (dopamine, opioids) and aversiveness (CRF, dynorphin), as well as intrinsic factors (personality, psychiatric co-morbidities) and extrinsic factors (history of abuse, environment especially peers and family) which influence the progression from initial use to abuse., Many of these important differences emerge during adolescence, and are moderated by sexual differentiation of the brain. Estradiol effects which enhance both dopaminergic and CRF-mediated processes contribute to the female vulnerability to substance use and abuse. Testosterone enhances impulsivity and sensation seeking in both males and females. Several protective factors in females also influence initiation and progression of substance use including hormonal changes of pregnancy as well as greater capacity for self-regulation and lower peak levels of impulsivity/sensation seeking. Same sex peers represent a risk factor more for males than females during adolescence, while romantic partners increase risk for women during this developmental epoch. In summary, biologic factors, psychiatric co-morbidities as well as personality and environment present sex/gender-specific risks as adolescents begin to initiate substance use.

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Section: Sex Differences In Intrinsic and Extrinsic Factors Contrimentioning

confidence: 99%

Emergence of sex differences in the development of substance use and abuse during adolescence

Kuhn

2015

Pharmacology & Therapeutics

148

109

View full text Add to dashboard Cite

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“…22,23 According to Lawson, Back, Hartwell, MoranSanta Maria et al 24 exposure to traumatic events is common among individuals with substance use disorders. Case 1 and 2 had experienced childhood abuse which has resulted in self-medicating against prior abuse issues with poly-substance use Khantzain.…”

Section: Case 2 Reportedmentioning

confidence: 99%

The Use of Cognitive Behavioural Therapy on Two Case Reports of Paraphilic Infantilism, Substance Misuse and Childhood Abuse

Banbury

Lusher

Athanasiadou-Lewis

et al. 2017

MOJAMT

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Abbreviations: APA, american psychiatric association; AB, adult baby; SB, sissy babies'; DL, diaper lovers; CBT, cognitive behavioral therapy; SSRIS, selective serotonin re-uptake inhibitors; PTSD, posttraumatic stress disorder Introduction: An overview of paraphilic infantilismParaphilia refers to the intense and persistent sexual interest and arousal towards objects, situations or individuals which are atypical, equal to and/or greater than normophilic sexual interests.1 Paraphilic disorders in the DSM-5 include exhibitionism, fetishism, peadophilia, sexual masochism, sexual sadism, transvestic fetishism and voyeurism possess a formal diagnostic criteria (APA, 2015). However, paraphilic infantilism is classified as a sexual disorder under, 'other specified paraphilic disorder'. 1 It was during the 1960's that reference to clients' exclusive wearing of diapers as a means of attaining sexual arousal became documented. Tuchman & Lachman 2 reported a child sex offender, who had been molesting his 4 and 6 year old daughters. He would wear rubber pants over his diaper and enjoyed urinating and masturbating in them. Malitz 3 describes a 20 year old male who had broken into a house with the sole intention of wearing diapers and defecating in them and subsequently reaching orgasm. Dinello 4 provided a diagnostic understanding of a 17 year old male who wore diapers, had eaten baby food, drank from a baby bottle and masturbated whilst wearing a diaper.During the 1980's, Money 5 termed the paraphilic condition of impersonating a baby, autonepiophilia, diaperism or paraphilic infantilism. Money 6 distinguished between infantilism, autonepiophilia and paraphilic diaper-wearing, stating that the latter is a paraphilic fetish involving an erotic attraction to an article of clothing whilst the former is a non-fetishistic paraphilia aimed at regressive age identity role play. Paraphilic infantilism was described as an individual acting as an infant including associated behaviours of drinking from a baby bottle, being fed baby food, being breast fed, wearing baby cloths, wearing diapers and sleeping in a crib. This may have involved the assistance of a 'nanny', 'daddy' or 'mommy' to accommodate the infantilists requirements. 6,7 When role play involves regressing back to an infant state the individual is referred to as an adult baby (AB). The AB's like to dress up as a baby, get baby fed, have diaper changes and so forth.7 'Sissy babies' (SB) are adults who also play the infant role however, the role played is the opposite gender and may involve cross dressing SBs. Those who only engage in wearing diapers, as a sexual fetish, without the regressive fantasies are referred to as diaper lovers (DL). 7Those who experience both the sexual aspect of wearing diapers and the enjoyment of engaging in infantile play are referred to as adult baby/diaper lovers (AB/DL). 7Money 6 also referred to paraphilic juvenilism or age play. Age Play predominately involves adults who role play at being babies, children or younger adults. Money 6 examin...

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“…Limited research links some traumatic events in childhood to non-medical use of prescription drugs (Khoury et al, 2010; Lawson et al, 2013; McCauley et al, 2010), and IDU has been linked to sexual (Ompad et al, 2005; Roy et al, 2003) and physical abuse (Kerr et al; 2009). A cumulative effect of trauma that extends past childhood has been documented (Dube et al, 2003; Felitti et al, 1998; Khoury et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

The relationships of childhood trauma and adulthood prescription pain reliever misuse and injection drug use

Quinn

Boone

Scheidell

et al. 2016

Drug and Alcohol Dependence

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Background We examined associations between childhood trauma and adulthood prescription pain reliever misuse (PPRM) and injection drug use (IDU) in a nationally-representative U.S. sample to further understanding of factors associated with these epidemics. Methods National Longitudinal Study of Adolescent to Adult Health data (N=12,288) yielded nine childhood traumas: neglect; emotional, physical, sexual abuse; parental incarceration and binge drinking; witnessed, threatened with, and experienced violence. We estimated adjusted odds ratios (AOR) and 95% confidence intervals for the association of each trauma and cumulative trauma and drug initiation in emerging and later adulthood. Results Outcome prevalences were 20% (PPRM) and 1% (IDU) in emerging adulthood and 10% PPRM in adulthood. We observed dose-response relationships that varied across outcomes. Cumulative trauma (referent=none) was associated with 34–79% greater odds of PPRM (emerging adulthood) across one to five+ trauma categories. The gradient was most consistent and associations strongest for adulthood PPRM: one trauma AOR=1.46(1.12, 1.91); two AOR=1.71(1.23, 2.36); three AOR=2.16(1.43, 2.36); four AOR=2.70(1.42, 5.62); five+ AOR=3.09(1.52, 6.30). Dose-response was less consistent for IDU, but 4 and 5+ traumas were associated with approximately seven and five times the odds of IDU. Neglect, emotional abuse, and parental incarceration and binge drinking were associated with 25–55% increased odds of PPRM. Sexual abuse and witnessed violence were associated with nearly 3 and 5 times the odds of IDU. Conclusions Associations between childhood trauma and PPRM/IDU highlight the need for trauma-informed interventions for drug users and early trauma screening and treatment for prevention of drug misuse over the life course.

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A Comparison of Trauma Profiles among Individuals with Prescription Opioid, Nicotine, or Cocaine Dependence

Cited by 79 publications

References 22 publications

Emergence of sex differences in the development of substance use and abuse during adolescence

Emergence of sex differences in the development of substance use and abuse during adolescence

The Use of Cognitive Behavioural Therapy on Two Case Reports of Paraphilic Infantilism, Substance Misuse and Childhood Abuse

The relationships of childhood trauma and adulthood prescription pain reliever misuse and injection drug use

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