A Comparison of Wedge and Needle Hepatic Biopsy in Open Bariatric Surgery

Padoin, Alexandre Vontobel; Mottin, Cláudio Corá; Moretto, Myriam; Berleze, Diovanne; Kupski, Carlos; Glock, Luiz; Reichel, Carlos Luiz; Silva, Vinícius Duval da; Silva, Jefferson Braga da

doi:10.1381/096089206775565159

Cited by 33 publications

(25 citation statements)

References 20 publications

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“…The discrepancy, therefore, between the shear wave velocity readings taken from the immediate subcapsular liver and that of the deeper parenchyma will result in a greater dispersion of results and hence less reliability. Interestingly, it is also well known that liver biopsies obtained from subcapsular regions in any part of the liver fail to accurately estimate the degree of fibrosis [23]. The intra-observer findings for all three operators concur with the results of the interobserver study, with measurements taken from segments 5/6 and 7/8 found to be the most reliable.…”

Section: Discussionsupporting

confidence: 77%

Acoustic radiation force impulse quantification: repeatability of measurements in selected liver segments and influence of age, body mass index and liver capsule-to-box distance

Jaffer

Lung²,

Bosanac³

et al. 2012

BJR

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Objective: To assess the inter-and intra-observer variability of acoustic radiation force impulse (ARFI) quantification in liver segments with influence of age, body mass index (BMI) and liver capsule-to-box (CB) distance. Methods: 10 healthy volunteers were examined twice, by three experienced operators, separated by a 1-week interval. 10 readings were obtained, from segments 3, 5/6 and 7/8. Age, BMI and the CB distance were noted. The Cronbach a statistic for analysis of reliability was performed for the inter-and intra-observer studies. Multivariate linear regression models determined significance of the other parameters. . For both the inter-and intra-observer study, the Cronbach a statistic was $0.7 (reliable) when taken from segments 5/6 and 7/8 but ,0.7 (unreliable) for segment 3. BMI and age showed significant (p,0.0001) but contrasting correlation (segment 5/6: BMI r50.02, age r520.02; segment 7/8: BMI r520.01, age r50.01) with ARFI velocities when analysed for the segments deemed reliable. A weak negative correlation between ARFI velocities and liver CB distance was demonstrated for both assessed segments (segment 5/6, r520.08; segment 7/8, r520.06; p,0.001). Conclusion: With trained operators, ARFI is a reliable and reproducible method of liver stiffness quantification in segments 5/6 and 7/8 but acquisition of measurements from segment 3 should be avoided. Values obtained deeper to the liver capsule allow more reliable liver stiffness quantification.

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Section: Discussionsupporting

confidence: 77%

Acoustic radiation force impulse quantification: repeatability of measurements in selected liver segments and influence of age, body mass index and liver capsule-to-box distance

Jaffer

Lung²,

Bosanac³

et al. 2012

BJR

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“…In the current study, 85% of the subjects were associated with NASH reported more scarcely in previous studies (14,(25)(26)(27)(28). This difference of prevalence is discussed further.…”

Section: Discussioncontrasting

confidence: 41%

Predictive Factors of Steatosis and Non-Alcoholic Steatohepatitis in Morbidly Obese Patients Undergoing Bariatric Surgery

et al. 2017

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Background and Objectives: Obesity is one of the most health-threatening phenomena. It is estimated that over 1 billion adults have overweight or obesity. The current study aimed at presenting a detailed account of the findings that attempted to predict the severity of fatty liver disease and its sequelae, including non-alcoholic steatohepatitis (NASH), fibrosis, and cirrhosis, by correlating biopsy results with liver function tests and various metabolic markers of laboratory results in patients with morbid obesity.

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“…One recent study found needle biopsies to be as effective as wedge biopsies in assessing the degree of steatosis in morbidly obese patients but that the presence of subcapsular fibrosis in needle biopsies was less than in wedge biopsies. 36 Older series report that both wedged and needle biopsy samples are appropriate for assessing the degree of fibrosis or cirrhosis. 37 Significant variability has been also observed between right and left lobe liver biopsies.…”

Section: Discussionmentioning

confidence: 99%

Routine Liver Biopsy to Screen for Nonalcoholic Fatty Liver Disease (NAFLD) during Cholecystectomy for Gallstone Disease: Is it Justified?

Medina¹,

Troche

Roesch-Dietlen

et al. 2008

Journal of Gastrointestinal Surgery

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A Comparison of Wedge and Needle Hepatic Biopsy in Open Bariatric Surgery

Abstract: Needle biopsies were as effective as wedge biopsies in assessing the degree of steatosis in morbidly obese patients. More important, the presence of subcapsular fibrosis in needle biopsies was less than in wedge biopsies, suggesting an adequate tissue sample by the less invasive technique.

Cited by 33 publications

References 20 publications

Acoustic radiation force impulse quantification: repeatability of measurements in selected liver segments and influence of age, body mass index and liver capsule-to-box distance

Acoustic radiation force impulse quantification: repeatability of measurements in selected liver segments and influence of age, body mass index and liver capsule-to-box distance

Predictive Factors of Steatosis and Non-Alcoholic Steatohepatitis in Morbidly Obese Patients Undergoing Bariatric Surgery

Routine Liver Biopsy to Screen for Nonalcoholic Fatty Liver Disease (NAFLD) during Cholecystectomy for Gallstone Disease: Is it Justified?

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